Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Lacunar infarction
ADR ID BADD_A04986
ADR Hierarchy
17      Nervous system disorders
17.08      Central nervous system vascular disorders
17.08.01      Central nervous system haemorrhages and cerebrovascular accidents
17.08.01.016      Lacunar infarction
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.06      Cerebrovascular and spinal necrosis and vascular insufficiency
24.04.06.009      Lacunar infarction
Description Stroke caused by lacunar infarction or other small vessel diseases of the brain. It features hemiparesis (see PARESIS), hemisensory, or hemisensory motor loss. | Brain infarction that affects small subcortical vessels due to occlusion of a penetrating artery deep in the brain. It may lead to lacunar stroke. [MeSH]
MedDRA Code 10051078
MeSH ID D059409
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Lacunar infarction | Lacunar infarcts in the basal ganglia | Stroke, Lacunar | Lacunar Stroke | Lacunar Strokes | Strokes, Lacunar | Lacunar Syndrome | Lacunar Syndromes | Syndrome, Lacunar | Syndromes, Lacunar | Infarction, Lacunar | Infarctions, Lacunar | Lacunar Infarction | Lacunar Infarctions | Infarct, Lacunar | Infarcts, Lacunar | Lacunar Infarct | Lacunar Infarcts
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000198%
BADD_D00121Amlodipine0.000006%
BADD_D00151Apixaban0.000174%
BADD_D00178Atenolol0.000019%
BADD_D00194Azacitidine0.000112%
BADD_D00229Benazeprilat-
BADD_D00312Bupropion0.000037%
BADD_D00337Calcitriol0.000223%
BADD_D00344Canagliflozin0.000180%
BADD_D00364Carboplatin0.000168%
BADD_D00466Cilostazol0.000900%
BADD_D00504Clopidogrel0.000064%
BADD_D00563Dabigatran0.001468%
BADD_D00680Dimethyl fumarate0.000400%
BADD_D00773Entacapone0.002744%
BADD_D00856Etoricoxib--
BADD_D00870Febuxostat--
BADD_D01008Gefitinib0.000112%
BADD_D01023Glimepiride0.000042%
BADD_D01119Ibrutinib0.000112%
BADD_D01136Imatinib0.000224%
BADD_D01300Lisinopril0.000007%
BADD_D01777Pioglitazone0.000086%
BADD_D01835Pregabalin0.000104%
BADD_D01888Quetiapine0.000055%
BADD_D01954Rivaroxaban0.000475%
BADD_D02029Sitagliptin0.000053%
BADD_D02105Tacrolimus0.000297%
BADD_D02170Testosterone0.001000%
BADD_D02337Varenicline0.000195%
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