| Drug Name |
Lisinopril |
| Drug ID |
BADD_D01300 |
| Description |
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs.[A184853] It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.[A184844]
Lisinopril was granted FDA approval on 29 December 1987.[L8384] |
| Indications and Usage |
For the treatment of hypertension and symptomatic congestive heart failure. May be used in conjunction with thrombolytic agents, aspirin and/or β-blockers to improve survival in hemodynamically stable individuals following myocardial infarction. May be used to slow the progression of renal disease in hypertensive patients with diabetes mellitus and microalbuminuria or overt nephropathy. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
C09AA03 |
| DrugBank ID |
DB00722
|
| KEGG ID |
D00362
|
| MeSH ID |
D017706
|
| PubChem ID |
5362119
|
| TTD Drug ID |
D07HGR
|
| NDC Product Code |
0615-8253; 69117-0037; 63187-775; 76282-418; 0615-8255; 50090-5122; 64220-142; 55289-884; 0615-8254; 68071-1775; 68788-6920; 61919-746; 68071-3123; 71335-0075; 0143-9715; 61919-717; 70518-1316; 0904-6799; 43353-993; 68071-1843; 72865-211; 72865-209; 68645-532; 68071-5190; 70518-1565; 63629-8082; 68071-1672; 63187-534; 65862-042; 0591-0409; 68788-7966; 64679-927; 51655-399; 43547-417; 53002-1178; 50090-2988; 50090-3774; 50436-0352; 43063-480; 43063-074; 55154-2128; 68001-336; 68084-196; 68071-5098; 68788-7831; 61919-942; 55154-8096; 64220-154; 68071-4858; 68071-4871; 42708-096; 68071-5077; 70882-110; 63187-722; 58118-1980; 42708-033; 76282-417; 43353-643; 71610-312; 0591-0408; 68071-3122; 50090-4678; 68001-333; 60760-357; 51655-411; 63629-1761; 60760-360; 52427-441; 64679-928; 50090-2228; 0143-9714; 0591-0885; 31722-179; 43353-297; 0591-0406; 42708-094; 64679-953; 67046-424; 71610-624; 55154-4682; 0185-0605; 50090-2934; 70518-1906; 68645-593; 61919-561; 43547-355; 65862-041; 70518-1156; 0591-0405; 51655-273; 50090-3763; 43547-418; 52427-439; 16729-380; 51655-232; 63187-442; 69117-0015; 68001-334; 43547-415; 71205-626; 0185-0640; 63629-7445; 68071-5143; 69117-0012; 72865-210; 72789-101; 43547-419; 71610-616; 50090-4485; 0904-6800; 65862-039; 65977-0009; 72865-213; 43547-356; 68788-7666; 0904-6797; 52652-3001; 0615-8256; 43547-354; 42708-142; 61919-736; 71610-612; 43063-814; 63187-098; 58118-1981; 50090-3765; 68180-517; 68180-981; 43353-009; 68071-1894; 0615-8252; 69117-0038; 68001-337; 53002-1123; 61919-721; 68071-5090; 71335-0498; 63629-2688; 0615-8405; 72789-093; 68788-7012; 35356-879; 71205-071; 43353-113; 63187-821; 0185-0610; 43353-298; 0591-0407; 68001-332; 50090-4725; 50090-4885; 72969-092; 54458-873; 61919-307; 50090-4887; 70518-3166; 43063-813; 68071-3178; 31722-178; 54458-874; 70518-0701; 68071-4931; 68645-552; 0185-0630; 68071-3043; 67296-1202; 52427-440; 60687-646; 68788-7746; 70518-2561; 65862-038; 43547-352; 15308-0800; 68071-2224; 70518-2600; 52427-443; 70518-2655; 43353-270; 70934-171; 68001-486; 70882-103; 60760-359; 71610-588; 69117-0014; 76282-420; 68084-199; 64679-941; 63629-8736; 71335-1426; 68788-6820; 68180-982; 63187-237; 68180-979; 67651-0225; 55700-547; 54458-872; 65862-037; 0904-7200; 16729-376; 71335-0015; 70934-120; 68645-550; 55154-4992; 72865-212; 51655-335; 65862-040; 43063-800; 0143-9713; 60687-678; 51655-292; 68180-513; 17404-0011; 65730-1301; 76282-421; 71610-536; 16729-379; 68788-6407; 64679-942; 0904-6798; 50436-0354; 70518-1790; 50090-2431; 68788-7334; 43063-815; 43353-301; 60760-455; 31722-172; 43547-414; 60760-380; 31722-176; 71335-0176; 55700-513; 72865-208; 63187-825; 63187-257; 16729-378; 61919-161; 70518-1665; 54458-877; 42708-031; 71335-0354; 68788-6811; 0185-0620; 71335-0536; 43063-786; 31722-180; 63187-780; 63187-099; 60760-358; 55154-2329; 43547-351; 43547-353; 68180-512; 60687-667; 70518-0134; 31722-177; 61919-909; 71205-180; 57297-511; 68645-553; 63629-8823; 50090-3175; 69117-0036; 43063-810; 68788-7633; 68071-5036; 76282-419; 71335-1295; 70934-200; 16729-375; 53002-1463; 50090-0808; 43063-811; 68071-5089; 55154-2131; 43063-769; 76282-422; 42708-032; 63629-5247; 70518-1152; 0185-0602; 71610-406; 70882-104; 71335-1380; 68645-555; 71610-638; 68071-4660; 70518-0117; 50090-4991; 60687-333; 68084-765; 67296-1249; 70518-0544; 70934-155; 60687-656; 68071-5046; 43353-793; 55154-8077; 63827-1012; 68180-980; 43353-662; 55154-8078; 60687-325; 68071-3064; 70518-0468; 68645-554; 16729-377; 50090-3757; 68071-3220; 70934-919; 53002-1225; 68001-335; 60760-390; 52427-438; 68645-587; 43547-416; 43353-271; 43063-812; 60760-438; 67296-1154; 71610-279; 52427-442; 64679-929; 71205-471; 68645-551; 55700-480 |
| Synonyms |
Lisinopril | Lysinopril | Lisinopril Sulfate (1:2) | Prinivil | Zestril | Lisinopril Maleate (1:1) | MK-521 |
