Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Ventricular fibrillation
ADR ID BADD_A04561
ADR Hierarchy
02      Cardiac disorders
02.03      Cardiac arrhythmias
02.03.04      Ventricular arrhythmias and cardiac arrest
02.03.04.008      Ventricular fibrillation
Description A disorder characterized by a dysrhythmia without discernible QRS complexes due to rapid repetitive excitation of myocardial fibers without coordinated contraction of the ventricles. [CTCAE] A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST. [MeSH]
MedDRA Code 10047290
MeSH ID D014693
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Fibrillation paroxysmal vent | Fibrillation ventricular | Paroxysmal ventricular fibrillation | Ventricular fibrillation | Ventricular fibrillation and flutter | Ventricular fibrillation paroxysm | Ventricular fibrillation paroxysmal | VF | Recurrent ventricular fibrillation | Ventricular Fibrillation | Fibrillation, Ventricular | Fibrillations, Ventricular | Ventricular Fibrillations
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00668Digoxin0.001758%
BADD_D00671Dihydroergotamine--
BADD_D00672Dihydroergotamine mesylate--
BADD_D00674Diltiazem0.000041%
BADD_D00686Diphenhydramine0.000336%
BADD_D00692Dipyridamole--
BADD_D00693Disopyramide--
BADD_D00701Dofetilide0.000651%
BADD_D00702Dolasetron--
BADD_D00715Doxacurium chloride--
BADD_D00716Doxapram--
BADD_D00717Doxapram hydrochloride--
BADD_D00718Doxazosin0.000169%
BADD_D00723Doxorubicin0.000224%
BADD_D00734Duloxetine0.000093%
BADD_D00755Eletriptan--
BADD_D00759Eltrombopag0.000229%
BADD_D00777Ephedrine--
BADD_D00782Epinephrine0.000403%
BADD_D00783Epinephrine bitartrate--
BADD_D00792Eptifibatide--
BADD_D00809Escitalopram0.000161%
BADD_D00813Esmolol--
BADD_D00902Flecainide0.000245%
BADD_D00912Fluconazole0.000157%
BADD_D00931Fluorouracil0.000643%
BADD_D00932Fluoxetine0.000039%
BADD_D00976Frovatriptan--
BADD_D00977Frovatriptan succinate--
BADD_D00979Furosemide0.000146%
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ADReCS-Target
ADR Term Drug Name Target