Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Doxacurium chloride
Drug ID BADD_D00715
Description Doxacurium chloride is a long-acting, nondepolarizing skeletal muscle relaxant for intravenous administration.
Indications and Usage Used to provide skeletal muscle relaxation as an adjunct to general anesthesia, for endotracheal intubation or to facilitate mechanical ventilation.
Marketing Status approved
ATC Code M03AC07
DrugBank ID DB01135
KEGG ID D00760
MeSH ID C049429
PubChem ID 60168
TTD Drug ID D0Y7TO
NDC Product Code Not Available
UNII M78TVM3G5Z
Synonyms doxacurium | doxacurium chloride | 2,2'-((1,4-dioxobutane-1,4-diyl)bis(oxypropane-3,1-diyl))bis(6,7,8-trimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolinium) dichloride | BW A938U | BW-A-938U | BW-A938U | BW-A 938U | Nuromax
Chemical Information
Molecular Formula C56H78Cl2N2O16
CAS Registry Number 83348-52-1
SMILES C[N+]1(CCC2=CC(=C(C(=C2C1CC3=CC(=C(C(=C3)OC)OC)OC)OC)OC)OC)CCCOC(=O)CCC(=O)OCCC[ N+]4(CCC5=CC(=C(C(=C5C4CC6=CC(=C(C(=C6)OC)OC)OC)OC)OC)OC)C.[Cl-].[Cl-]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Bronchospasm10.01.03.012; 22.03.01.004--
Diplopia06.02.06.002; 17.17.01.005---
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Hypotension24.06.03.002--
Injection site reaction08.02.03.014; 12.07.03.015--
Myocardial infarction02.02.02.007; 24.04.04.009--
Pyrexia08.05.02.003--
Urticaria10.01.06.001; 23.04.02.001--
Ventricular fibrillation02.03.04.008--
Wheezing22.03.01.009--
Neuromuscular blockade reversal25.01.03.002---
Therapeutic product effect prolonged08.06.01.054---
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