Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Frovatriptan
Drug ID BADD_D00976
Description Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.
Indications and Usage For the acute treatment of migraine attacks with or without aura in adults.
Marketing Status approved; investigational
ATC Code N02CC07
DrugBank ID DB00998
KEGG ID D07997
MeSH ID C108128
PubChem ID 77992
TTD Drug ID D06FPQ
NDC Product Code Not Available
UNII H82Q2D5WA7
Synonyms frovatriptan | 3-methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole | Frova | VML-251 | VML251 | Frovelan | SB 209509 | Allegro | frovatriptan succinate | (+)-(R)-5,6,7,8-tetrahydro-6-(methylamino)carbazole-3-carboxamide succinate (1:1), monohydrate
Chemical Information
Molecular Formula C14H17N3O
CAS Registry Number 158747-02-5
SMILES CNC1CCC2=C(C1)C3=C(N2)C=CC(=C3)C(=O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agitation17.02.05.012; 19.06.02.001--
Amnesia17.03.02.001; 19.20.01.001--
Anaphylactic shock10.01.07.002; 24.06.02.004---
Anxiety19.06.02.002--
Arrhythmia02.03.02.001---
Arteriospasm coronary02.02.02.005; 12.02.01.031; 24.04.04.005---
Arthralgia15.01.02.001--
Arthropathy15.01.01.003---
Asthenia08.01.01.001---
Ataxia08.01.02.004; 17.02.02.001--
Back pain15.03.04.005--
Blood pressure increased13.14.03.005---
Body temperature increased13.15.01.001---
Bone pain15.02.01.001--
Bradycardia02.03.02.002---
Cardiovascular disorder02.11.01.010; 24.03.02.009---
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Change of bowel habit07.02.03.002---
Cheilitis07.05.01.001; 23.03.03.025--
Chest discomfort02.02.02.009; 08.01.08.019; 22.12.02.002---
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Chills08.01.09.001; 15.05.03.016--
Coagulopathy01.01.02.001---
Confusional state17.02.03.005; 19.13.01.001--
Conjunctivitis06.04.01.002; 11.01.06.012--
Constipation07.02.02.001--
Dehydration14.05.05.001--
Depression19.15.01.001--
Dermatitis bullous23.03.01.002--
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