Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Ventricular fibrillation
ADR ID BADD_A04561
ADR Hierarchy
02      Cardiac disorders
02.03      Cardiac arrhythmias
02.03.04      Ventricular arrhythmias and cardiac arrest
02.03.04.008      Ventricular fibrillation
Description A disorder characterized by a dysrhythmia without discernible QRS complexes due to rapid repetitive excitation of myocardial fibers without coordinated contraction of the ventricles. [CTCAE] A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST. [MeSH]
MedDRA Code 10047290
MeSH ID D014693
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Fibrillation paroxysmal vent | Fibrillation ventricular | Paroxysmal ventricular fibrillation | Ventricular fibrillation | Ventricular fibrillation and flutter | Ventricular fibrillation paroxysm | Ventricular fibrillation paroxysmal | VF | Recurrent ventricular fibrillation | Ventricular Fibrillation | Fibrillation, Ventricular | Fibrillations, Ventricular | Ventricular Fibrillations
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00309Bupivacaine hydrochloride--
BADD_D00312Bupropion0.000110%
BADD_D00328Cabazitaxel--
BADD_D00332Caffeine0.000139%
BADD_D00347Candesartan cilexetil0.000841%
BADD_D00348Cangrelor0.000123%
BADD_D00349Capecitabine0.006100%
BADD_D00356Carbamazepine0.000279%
BADD_D00364Carboplatin0.000302%
BADD_D00374Carvedilol--
BADD_D00382Cefazolin0.000049%
BADD_D00405Ceftriaxone0.031196%
BADD_D00407Cefuroxime0.000143%
BADD_D00410Celecoxib--
BADD_D00440Chloroquine0.000283%
BADD_D00466Cilostazol0.000600%
BADD_D00471Ciprofloxacin--
BADD_D00475Citalopram0.000038%
BADD_D00480Clarithromycin0.000558%
BADD_D00499Clomipramine--
BADD_D00504Clopidogrel0.000075%
BADD_D00511Clozapine--
BADD_D00549Cyclophosphamide--
BADD_D00560Cytarabine0.000280%
BADD_D00612Desipramine--
BADD_D00613Desipramine hydrochloride--
BADD_D00623Dexamethasone0.000363%
BADD_D00629Dexmedetomidine0.000457%
BADD_D00646Diatrizoate sodium--
BADD_D00647Diatrizoic acid--
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ADReCS-Target
ADR Term Drug Name Target