Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Sciatica
ADR ID BADD_A03932
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.10      Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)
15.10.01      Intervertebral disc disorders NEC
15.10.01.001      Sciatica
17      Nervous system disorders
17.10      Spinal cord and nerve root disorders
17.10.03      Lumbar spinal cord and nerve root disorders
17.10.03.001      Sciatica
Description A condition characterized by pain radiating from the back into the buttock and posterior/lateral aspects of the leg. Sciatica may be a manifestation of SCIATIC NEUROPATHY; RADICULOPATHY (involving the SPINAL NERVE ROOTS; L4, L5, S1, or S2, often associated with INTERVERTEBRAL DISK DISPLACEMENT); or lesions of the CAUDA EQUINA. [MeSH]
MedDRA Code 10039674
MeSH ID D012585; D012585; D012585
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Cotunnius' disease | Ischial neuralgia | Ischias | Lumbosacral root pain | Neuritis sciatic | R sciatica | Sciatic neuralgia | Sciatica | Sciatica (excl lumbar disc lesion) | Sciatica aggravated | Lumboischialgia | Cruralgia | Ischialgia | Lumbar root pain | Cotugno's disease | Lumbar radicular pain | Lumbocrural pain | Lumbosciatalgia | Sciatic Neuralgia | Neuralgia, Sciatic | Neuralgias, Sciatic | Sciatic Neuralgias | Sciatica, Bilateral | Bilateral Sciatica | Bilateral Sciaticas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00023Acetaminophen--
BADD_D00066Alendronic acid0.001189%
BADD_D00069Alfuzosin--
BADD_D00142Anastrozole0.000238%
BADD_D00165Aripiprazole0.000119%
BADD_D00166Aripiprazole lauroxil-
BADD_D00193Axitinib0.000246%
BADD_D00195Azathioprine--
BADD_D00209Baclofen0.000104%
BADD_D00271Bicalutamide0.002109%
BADD_D00284Bortezomib0.000112%
BADD_D00285Bosentan0.000951%
BADD_D00286Bosutinib0.000627%
BADD_D00306Budesonide--
BADD_D00312Bupropion--
BADD_D00314Bupropion hydrochloride--
BADD_D00328Cabazitaxel--
BADD_D00516Codeine0.000343%
BADD_D00535Crizotinib0.000246%
BADD_D00608Denosumab--
BADD_D00623Dexamethasone0.000291%
BADD_D00680Dimethyl fumarate0.002841%
BADD_D00732Droxidopa0.000288%
BADD_D00809Escitalopram--
BADD_D00856Etoricoxib--
BADD_D00858Everolimus0.000229%
BADD_D00898Finasteride0.000090%
BADD_D00931Fluorouracil0.000184%
BADD_D00978Fulvestrant0.001702%
BADD_D00981Gabapentin0.000117%
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