Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Respiratory failure
ADR ID BADD_A03813
ADR Hierarchy
14      Metabolism and nutrition disorders
14.01      Acid-base disorders
14.01.04      Respiratory acidoses
14.01.04.003      Respiratory failure
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.06      Respiratory failures (excl neonatal)
22.02.06.002      Respiratory failure
Description A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. [CTCAE] Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) [MeSH]
MedDRA Code 10038695
MeSH ID D012131
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Failure respiratory | Other pulmonary insufficiency, not elsewhere classified | Pulmonary insufficiency following trauma and surgery | Respiration failure | Respiratory failure | Respiratory failure (excl neonatal) | Respiratory insufficiency | Ventilatory failure | Pulmonary failure | Hypercapnic respiratory failure | Restrictive respiratory insufficiency | Respiratory failure aggravated | Hypoxic respiratory failure | End stage lung disease | Respiratory failure type 1 | Respiratory failure type 2 | Hypoxemic respiratory failure | Hypoxaemic respiratory failure | Respiratory Insufficiency | Respiratory Failure | Respiratory Depression | Ventilatory Depression | Depressions, Ventilatory
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00701Dofetilide0.000169%
BADD_D00711Dornase alfa--
BADD_D00716Doxapram--
BADD_D00718Doxazosin0.000113%
BADD_D00723Doxorubicin0.000839%
BADD_D00730Dronedarone0.001225%
BADD_D00736Dutasteride0.000341%
BADD_D00761Eluxadoline--
BADD_D00768Enalaprilat0.010131%
BADD_D00782Epinephrine--
BADD_D00784Epirubicin0.000168%
BADD_D00788Epoprostenol0.000987%
BADD_D00800Erlotinib0.001903%
BADD_D00802Ertapenem0.000073%
BADD_D00813Esmolol--
BADD_D00851Etomidate--
BADD_D00854Etoposide0.000504%
BADD_D00858Everolimus0.003058%
BADD_D00869Famotidine0.000091%
BADD_D00871Felbamate--
BADD_D00879Fentanyl--
BADD_D00880Fentanyl citrate--
BADD_D00886Ferrosoferric oxide--
BADD_D00890Ferumoxytol non-stoichiometric magnetite-
BADD_D00914Fludarabine0.000672%
BADD_D00915Fludarabine phosphate--
BADD_D00926Fluorescein0.000107%
BADD_D00931Fluorouracil0.002206%
BADD_D00932Fluoxetine0.000177%
BADD_D00946Fluticasone furoate--
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