Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Myoclonus
ADR ID BADD_A02940
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.05      Neurological signs and symptoms NEC
17.02.05.008      Myoclonus
Description Involuntary shock-like contractions, irregular in rhythm and amplitude, followed by relaxation, of a muscle or a group of muscles. This condition may be a feature of some CENTRAL NERVOUS SYSTEM DISEASES; (e.g., EPILEPSY, MYOCLONIC). Nocturnal myoclonus is the principal feature of the NOCTURNAL MYOCLONUS SYNDROME. (From Adams et al., Principles of Neurology, 6th ed, pp102-3). [MeSH]
MedDRA Code 10028622
MeSH ID D009207
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Myclonic jerks | Myoclonic jerks | Myoclonus | Palatal myoclonus | Negative myoclonus | Positive myoclonus | Hypnagogic myoclonus | Hypnic jerk | Myoclonic Jerking | Jerking, Myoclonic | Myoclonic Jerk | Jerk, Myoclonic | Jerks, Myoclonic | Myoclonic Jerks | Myoclonus Simplex | Simplex, Myoclonus | Myoclonus, Action | Action Myoclonus | Myoclonus, Eyelid | Eyelid Myoclonus | Myoclonus, Intention | Intention Myoclonus | Myoclonus, Upper Extremity | Extremity Myoclonus, Upper | Upper Extremity Myoclonus | Polymyoclonus | Myoclonus, Nocturnal | Nocturnal Myoclonus | Myoclonus, Sleep | Sleep Myoclonus | Myoclonus, Oculopalatal | Oculopalatal Myoclonus | Myoclonus, Palatal | Palatal Myoclonus | Myoclonus, Segmental | Segmental Myoclonus | Myoclonus, Lower Extremity | Extremity Myoclonus, Lower | Lower Extremity Myoclonus
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00933Fluoxetine hydrochloride--
BADD_D00950Fluvoxamine--
BADD_D00951Fluvoxamine maleate--
BADD_D00970Fosphenytoin--
BADD_D00971Fosphenytoin sodium--
BADD_D00979Furosemide0.000049%
BADD_D00981Gabapentin0.001215%
BADD_D00982Gabapentin enacarbil-
BADD_D00996Galantamine0.003209%
BADD_D01003Ganciclovir--
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01096Hydromorphone0.000463%
BADD_D01102Hydroxybutanoic acid--
BADD_D01133Ifosfamide0.000280%
BADD_D01139Imipramine--
BADD_D01202Isocarboxazid--
BADD_D01223Ixazomib0.001679%
BADD_D01228Ketamine0.000179%
BADD_D01231Ketoprofen0.002240%
BADD_D01238Lacosamide0.009361%
BADD_D01243Lamotrigine0.002025%
BADD_D01252Leflunomide0.000428%
BADD_D01265Levetiracetam0.002202%
BADD_D01272Levocetirizine--
BADD_D01275Levofloxacin0.001210%
BADD_D01295Linezolid0.002470%
BADD_D01301Lisuride--
BADD_D01303Lithium carbonate0.003587%
BADD_D01304Lithium cation0.001728%
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