| Pharmaceutical Information |
| Drug Name |
Levocetirizine |
| Drug ID |
BADD_D01272 |
| Description |
Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of [cetirizine].[L7694] Levocetirizine has greater affinity for the histamine H1 receptor than cetirizine.[L7694]
Levocetirizine was granted FDA approval in 1995.[L7694] |
| Indications and Usage |
Levocetirizine is indicated to treat symptoms of perennial allergic rhinitis and uncomplicated skin manifestations of chronic idiopathic urticaria.[L7694] It is also used over the counter for a variety of mild allergy symptoms.[A181748] |
| Marketing Status |
approved |
| ATC Code |
R06AE09 |
| DrugBank ID |
DB06282
|
| KEGG ID |
D07402
|
| MeSH ID |
C472067
|
| PubChem ID |
1549000
|
| TTD Drug ID |
D0M8PW
|
| NDC Product Code |
Not Available |
| UNII |
6U5EA9RT2O
|
| Synonyms |
levocetirizine | levocetrizine | acetic acid, (2-(4-((R)-(4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)- | (2-(4-((R)-p-chloro-alpha-phenylbenzyl)-1-piperazinyl)ethoxy)acetic acid | levocetirizine hydrochloride | Xusal | levocetirizine dihydrochloride | (2-(4-((R)-(4-chlorophenyl)phenylmethyl)piperazin-1-yl)ethoxy)acetic acid dihydrochloride | cetirizine (R)-form dihydrochloride | acetic acid, (2-(4-((R)-(4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-, dihydrochloride | Xyzal | UCB-28556 |
|
| Chemical Information |
| Molecular Formula |
C21H25ClN2O3 |
| CAS Registry Number |
130018-77-8 |
| SMILES |
C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl |
| Chemical Structure |
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| ADRs Induced by Drug |
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