Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Myoclonus
ADR ID BADD_A02940
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.05      Neurological signs and symptoms NEC
17.02.05.008      Myoclonus
Description Involuntary shock-like contractions, irregular in rhythm and amplitude, followed by relaxation, of a muscle or a group of muscles. This condition may be a feature of some CENTRAL NERVOUS SYSTEM DISEASES; (e.g., EPILEPSY, MYOCLONIC). Nocturnal myoclonus is the principal feature of the NOCTURNAL MYOCLONUS SYNDROME. (From Adams et al., Principles of Neurology, 6th ed, pp102-3). [MeSH]
MedDRA Code 10028622
MeSH ID D009207
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Myclonic jerks | Myoclonic jerks | Myoclonus | Palatal myoclonus | Negative myoclonus | Positive myoclonus | Hypnagogic myoclonus | Hypnic jerk | Myoclonic Jerking | Jerking, Myoclonic | Myoclonic Jerk | Jerk, Myoclonic | Jerks, Myoclonic | Myoclonic Jerks | Myoclonus Simplex | Simplex, Myoclonus | Myoclonus, Action | Action Myoclonus | Myoclonus, Eyelid | Eyelid Myoclonus | Myoclonus, Intention | Intention Myoclonus | Myoclonus, Upper Extremity | Extremity Myoclonus, Upper | Upper Extremity Myoclonus | Polymyoclonus | Myoclonus, Nocturnal | Nocturnal Myoclonus | Myoclonus, Sleep | Sleep Myoclonus | Myoclonus, Oculopalatal | Oculopalatal Myoclonus | Myoclonus, Palatal | Palatal Myoclonus | Myoclonus, Segmental | Segmental Myoclonus | Myoclonus, Lower Extremity | Extremity Myoclonus, Lower | Lower Extremity Myoclonus
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00472Ciprofloxacin hydrochloride--
BADD_D00474Cisplatin--
BADD_D00475Citalopram0.000019%
BADD_D00476Citalopram hydrobromide--
BADD_D00488Clobazam0.000196%
BADD_D00499Clomipramine0.004250%
BADD_D00500Clomipramine hydrochloride--
BADD_D00501Clonazepam0.000110%
BADD_D00511Clozapine0.042556%
BADD_D00542Cyanocobalamin0.000127%
BADD_D00581Daptomycin0.000049%
BADD_D00648Diazepam0.000151%
BADD_D00657Dicloxacillin--
BADD_D00668Digoxin0.000158%
BADD_D00686Diphenhydramine0.000470%
BADD_D00706Donepezil0.000860%
BADD_D00734Duloxetine0.000240%
BADD_D00735Duloxetine hydrochloride--
BADD_D00802Ertapenem0.000365%
BADD_D00803Ertapenem sodium--
BADD_D00809Escitalopram0.000118%
BADD_D00810Escitalopram oxalate--
BADD_D00821Estradiol0.000031%
BADD_D00842Ethambutol hydrochloride--
BADD_D00851Etomidate0.000572%
BADD_D00865Ezogabine--
BADD_D00879Fentanyl0.000571%
BADD_D00880Fentanyl citrate--
BADD_D00902Flecainide0.000245%
BADD_D00932Fluoxetine0.000108%
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