Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hypopituitarism
ADR ID BADD_A02207
ADR Hierarchy
05      Endocrine disorders
05.03      Hypothalamus and pituitary gland disorders
05.03.02      Anterior pituitary hypofunction
05.03.02.001      Hypopituitarism
Description A disorder characterized by a decrease in production of hormones from the pituitary gland. [CTCAE] Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including LH; FOLLICLE STIMULATING HORMONE; SOMATOTROPIN; and CORTICOTROPIN). This may result from surgical or radiation ablation, non-secretory PITUITARY NEOPLASMS, metastatic tumors, infarction, PITUITARY APOPLEXY, infiltrative or granulomatous processes, and other conditions. [MeSH]
MedDRA Code 10021067
MeSH ID D007018
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Hypopituitalism | Hypopituitarism | Insufficiency pituitary | Panhypopituitarism | Pituitary activity decreased | Pituitary function depression | Pituitary hormone deficiency | Pituitary insufficiency | Pituitary Insufficiency | Insufficiency, Pituitary | Hyposecretion Syndrome, Anterior Pituitary | Hyposecretion, Adenohypophyseal | Adenohypophyseal Hyposecretion | Anterior Pituitary Hyposecretion Syndrome | Postpartum Hypopituitarism | Hypopituitarism, Postpartum | Simmonds' Disease | Simmond's Disease | Sheehan Syndrome | Syndrome, Sheehan | Postpartum Panhypopituitarism | Panhypopituitarism, Postpartum | Postpartum Pituitary Insufficiency | Pituitary Insufficiency, Postpartum | Sheehan's Syndrome | Sheehans Syndrome | Syndrome, Sheehan's | Simmonds Disease | Disease, Simmonds
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00082Alosetron--
BADD_D00083Alosetron hydrochloride--
BADD_D00260Betamethasone--
BADD_D00271Bicalutamide0.001406%
BADD_D00330Cabozantinib0.000470%
BADD_D00364Carboplatin0.000168%
BADD_D00511Clozapine0.001223%
BADD_D00623Dexamethasone0.000363%
BADD_D00653Diclofenac0.000026%
BADD_D00898Finasteride0.000090%
BADD_D00918Fludrocortisone acetate--
BADD_D00932Fluoxetine0.000049%
BADD_D00947Fluticasone propionate0.000276%
BADD_D01022Gliclazide--
BADD_D01030Glyburide--
BADD_D01091Hydrocortisone sodium succinate--
BADD_D01167Interferon alfa-2b--
BADD_D01190Ipilimumab--
BADD_D01260Leuprolide acetate0.001434%
BADD_D01285Levothyroxine0.000007%
BADD_D01366Medroxyprogesterone acetate--
BADD_D01433Methylprednisolone--
BADD_D01434Methylprednisolone acetate--
BADD_D01436Methylprednisolone sodium succinate--
BADD_D01684Pasireotide--
BADD_D01831Prednisolone--
BADD_D01832Prednisolone acetate--
BADD_D01833Prednisolone sodium phosphate--
BADD_D01834Prednisone--
BADD_D01933Ribavirin0.005934%
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