Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Methylprednisolone sodium succinate
Drug ID BADD_D01436
Description A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Indications and Usage Not Available
Marketing Status approved
ATC Code Not Available
DrugBank ID DB14644
KEGG ID D00751
MeSH ID D008776
PubChem ID 23680530
TTD Drug ID Not Available
NDC Product Code 0404-9957; 71872-7061; 0009-0003; 0009-0047; 0143-9754; 43598-129; 0009-0698; 52584-039; 52584-047; 0009-0850; 55150-263; 55154-3940; 55154-3941; 63323-255; 43598-128; 70518-2023; 0143-9850; 63323-265; 0404-9958; 71872-7232; 55150-262; 55150-265; 70518-3684; 0009-0039; 0143-9753; 71872-7085; 0143-9851; 55154-3939; 55154-3944; 43598-127; 50090-0271; 63323-258; 0009-0018; 43598-130; 0009-0758; 55150-264
UNII LEC9GKY20K
Synonyms Methylprednisolone Hemisuccinate | Hemisuccinate, Methylprednisolone | Methylprednisolone Succinate | Succinate, Methylprednisolone | Urbason-Soluble | UrbasonSoluble | Solu-Medrol | Solumedrol | A-MethaPred | Methylprednisolone Sodium Succinate | Sodium Succinate, Methylprednisolone | Methylprednisolone Hemisuccinate Monosodium Salt | 6 alpha-Methylprednisolone Sodium Hemisuccinate | Methylprednisolone Sodium Hemisuccinate | Sodium Hemisuccinate, Methylprednisolone
Chemical Information
Molecular Formula C26H33NaO8
CAS Registry Number 2375-03-3
SMILES CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)COC(=O)CCC(=O)[O-])O.[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abscess sterile08.01.05.008---
Acne23.02.01.001---
Alkalosis hypokalaemic14.01.02.002---
Alopecia23.02.02.001--
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anaphylactoid reaction10.01.07.003; 24.06.03.007---
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Arrhythmia02.03.02.001---
Bradycardia02.03.02.002---
Calcinosis08.03.04.002---
Carbohydrate tolerance decreased13.02.02.003---
Cardiac arrest02.03.04.001--
Cardiac failure congestive02.05.01.002---
Cardiomegaly02.04.02.001---
Cataract subcapsular06.06.01.002---
Circulatory collapse24.06.02.001---
Cushingoid05.01.01.002; 14.11.01.006; 19.07.03.001; 24.08.02.004--
Depression19.15.01.001--
Dermatitis allergic10.01.03.014; 23.03.04.003---
Diabetes mellitus05.06.01.001; 14.06.01.001---
Dry skin23.03.03.001--
Ecchymosis01.01.03.001; 23.06.01.001; 24.07.06.002---
Erythema23.03.06.001---
Euphoric mood19.04.02.006--
Exophthalmos05.02.02.002; 06.09.04.001---
Fat embolism12.01.08.003; 24.01.01.012---
Fluid retention14.05.06.002; 20.01.02.003---
Glaucoma06.03.01.002--
Glucose tolerance decreased13.02.02.004---
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