Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00147Antihemophilic factor (recombinant)--
BADD_D00152Apomorphine--
BADD_D00153Apomorphine hydrochloride--
BADD_D00154Apraclonidine--
BADD_D00155Apraclonidine hydrochloride--
BADD_D00156Apremilast--
BADD_D00157Aprepitant--
BADD_D00159Arformoterol--
BADD_D00160Arformoterol tartrate--
BADD_D00165Aripiprazole--
BADD_D00166Aripiprazole lauroxil-
BADD_D00167Armodafinil0.011049%
BADD_D00168Arsenic--
BADD_D00169Arsenic trioxide--
BADD_D00171Ascorbic acid0.004610%
BADD_D00172Asenapine--
BADD_D00173Asenapine maleate--
BADD_D00176Atazanavir--
BADD_D00178Atenolol--
BADD_D00179Atezolizumab--
BADD_D00180Atomoxetine--
BADD_D00181Atomoxetine hydrochloride--
BADD_D00182Atorvastatin calcium--
BADD_D00183Atorvastatin calcium propylene glycol--
BADD_D00184Atorvastatin calcium trihydrate--
BADD_D00189Atropine--
BADD_D00190Atropine sulfate--
BADD_D00192Avanafil--
BADD_D00193Axitinib0.092598%
BADD_D00194Azacitidine--
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ADReCS-Target
ADR Term Drug Name Target