Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Antihemophilic factor (recombinant)
Drug ID BADD_D00147
Description Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Indications and Usage For the treatment of hemophilia A, von Willebrand disease and Factor XIII deficiency.
Marketing Status approved; investigational
ATC Code Not Available
DrugBank ID DB00025
KEGG ID D05401
MeSH ID C078147
PubChem ID Not Available
TTD Drug ID Not Available
NDC Product Code 58394-015; 58394-024; 58394-012; 58394-022; 0944-3054; 68982-139; 68982-145; 68982-147; 0026-3787; 0026-3824; 68982-143; 68982-151; 58394-013; 0944-3047; 0026-3786; 0944-3046; 58394-014; 58394-016; 58394-023; 68982-141; 0026-3821; 0026-3822; 0026-3826; 0026-3828; 68982-149; 0026-3785; 68982-153; 0944-3053; 0944-3045; 0944-3051; 0944-3052; 58394-025; 0026-3782; 0026-3783
UNII Not Available
Synonyms F8 protein, human | antihemophilic factor human | factor VIII, human | coagulation factor VIII, human | coagulation factor VIII, procoagulant component (hemophilia A) protein, human | FVIII protein, human | BAY 81-8973 | F8B protein, human | Bioclate | Hemofil | Hemofil M | Hemophil | Hemofil HM | Kogenate FS | Kogenate | Monoclate | Recombinate | xyntha | Kovaltry | octocog alfa | Humate-P
Chemical Information
Molecular Formula Not Available
CAS Registry Number 139076-62-3
SMILES Not Available
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Acoustic stimulation tests abnormal13.07.08.001---
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Chest discomfort02.02.02.009; 08.01.08.019; 22.12.02.002---
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Chills08.01.09.001; 15.05.03.016--
Cough22.02.03.001--
Cyanosis02.11.04.004; 22.02.02.007; 23.06.04.005; 24.03.01.007--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dyspnoea02.11.05.003; 22.02.01.004--
Ear infection04.03.01.006; 11.01.05.001---
Epistaxis22.04.03.001; 24.07.01.005--
Erythema23.03.06.001---
Fatigue08.01.01.002--
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Haematoma24.07.01.001--
Headache17.14.01.001--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypersensitivity10.01.03.003--
Hypotension24.06.03.002--
Injection site reaction08.02.03.014; 12.07.03.015--
Laryngeal oedema10.01.05.003; 22.04.02.001; 23.04.01.005--
Laryngeal pain22.12.03.010--
Loss of consciousness17.02.04.004---
Malaise08.01.01.003--
Nausea07.01.07.001--
Pain in extremity15.03.04.010--
Pallor08.01.03.032; 23.03.03.031; 24.03.04.001---
Paraesthesia17.02.06.005; 23.03.03.094--
The 1th Page    1 2    Next   Last    Total 2 Pages