Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Calcinosis
ADR ID BADD_A00743
ADR Hierarchy
08      General disorders and administration site conditions
08.03      Tissue disorders NEC
08.03.04      Trophic disorders
08.03.04.002      Calcinosis
Description Pathologic deposition of calcium salts in tissues. | An extremely rare benign condition characterized by large calcified periarticular soft tissue masses composed of calcium salts, usually located around large joints. Tumoral calcinosis can occur due to HYPERPHOSPHATEMIA in patients with UREMIA and/or who are undergoing RENAL DIALYSIS. [MeSH]
MedDRA Code 10006938
MeSH ID D002114
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Calcification and ossification, unspecified | Calcinosis | Calcium deposits | Deposit calcium | Tissue calcification NOS | Tumoral calcinosis | Tumoural calcinosis | Calcinoses | Calcification, Pathologic | Pathologic Calcification | Microcalcification | Microcalcifications | Microcalcinosis | Microcalcinoses | Calcinosis, Tumoral | Calcinoses, Tumoral | Tumoral Calcinoses | Tumoral Calcinosis
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000110%
BADD_D00121Amlodipine--
BADD_D00174Asfotase alfa--
BADD_D00260Betamethasone--
BADD_D00337Calcitriol0.000447%
BADD_D00338Calcium acetate--
BADD_D00341Calcium ion--
BADD_D00722Doxercalciferol--
BADD_D00794Ergocalciferol--
BADD_D00821Estradiol--
BADD_D00898Finasteride0.000045%
BADD_D00974Fragmin--
BADD_D01117Ibandronic acid0.000697%
BADD_D01253Lenalidomide0.002291%
BADD_D01281Levonorgestrel0.001844%
BADD_D01336Macitentan0.000265%
BADD_D01433Methylprednisolone--
BADD_D01434Methylprednisolone acetate--
BADD_D01436Methylprednisolone sodium succinate--
BADD_D01676Paricalcitol--
BADD_D01954Rivaroxaban0.000139%
BADD_D02029Sitagliptin0.000053%
BADD_D02035Sodium carbonate--
BADD_D02105Tacrolimus0.000297%
BADD_D02236Tofacitinib0.001832%
BADD_D02247Topiramate--
BADD_D02271Triamcinolone--
BADD_D02272Triamcinolone acetonide--
BADD_D02273Triamcinolone diacetate--
BADD_D02274Triamcinolone hexacetonide--
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