Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Atrioventricular block first degree
ADR ID BADD_A00378
ADR Hierarchy
02      Cardiac disorders
02.03      Cardiac arrhythmias
02.03.01      Cardiac conduction disorders
02.03.01.004      Atrioventricular block first degree
Description A disorder characterized by a dysrhythmia with a delay in the time required for the conduction of an electrical impulse through the atrioventricular (AV) node beyond 0.2 seconds; prolongation of the PR interval greater than 200 milliseconds. [CTCAE]
MedDRA Code 10003674
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
1st degree heart block | Atrioventricular block first degree | Atrioventricular conduction time prolonged | AV block first degree | First degree atrioventricular block | Heart block 1st degree | Heart block AV first degree | Heart block first degree
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00037Aclidinium bromide--
BADD_D00045Adenosine--
BADD_D00066Alendronic acid0.000220%
BADD_D00085Alprazolam0.000019%
BADD_D00115Amiodarone0.000539%
BADD_D00121Amlodipine0.000006%
BADD_D00165Aripiprazole0.000079%
BADD_D00178Atenolol0.000078%
BADD_D00209Baclofen0.000139%
BADD_D00254Bepridil--
BADD_D00277Bisoprolol0.002041%
BADD_D00374Carvedilol0.000073%
BADD_D00502Clonidine0.000045%
BADD_D00511Clozapine0.010028%
BADD_D00602Delamanid--
BADD_D00629Dexmedetomidine0.000131%
BADD_D00648Diazepam0.000050%
BADD_D00668Digoxin0.000947%
BADD_D00674Diltiazem0.000143%
BADD_D00675Diltiazem hydrochloride--
BADD_D00702Dolasetron--
BADD_D00706Donepezil0.000402%
BADD_D00733Dulaglutide--
BADD_D00809Escitalopram0.000038%
BADD_D00869Famotidine0.000204%
BADD_D00899Fingolimod hydrochloride--
BADD_D00902Flecainide0.000367%
BADD_D00932Fluoxetine--
BADD_D00964Foscarnet sodium--
BADD_D00979Furosemide0.000028%
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ADReCS-Target
ADR Term Drug Name Target