Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dabigatran
Drug ID BADD_D00563
Description Dabigatran is the active form of the orally bioavailable prodrug [dabigatran etexilate].
Indications and Usage Not Available
Marketing Status approved; investigational
ATC Code B01AE07
DrugBank ID DB14726
KEGG ID D09707
MeSH ID D000069604
PubChem ID 216210
TTD Drug ID D0M7JT
NDC Product Code 51869-0030
UNII I0VM4M70GC
Synonyms Dabigatran | N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine | BIBR 1048 | Pradaxa | Dabigatran Etexilate | Etexilate, Dabigatran | Dabigatran Etexilate Mesylate | Etexilate Mesylate, Dabigatran | Mesylate, Dabigatran Etexilate
Chemical Information
Molecular Formula C25H25N7O3
CAS Registry Number 211914-51-1
SMILES CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Aphasia17.02.03.001; 19.21.01.0010.016074%
Apraxia17.02.03.002; 19.21.01.0020.000856%-
Arterial thrombosis24.01.01.0020.002569%-
Arteriosclerosis coronary artery02.02.01.011; 24.04.04.0120.000367%-
Arteriovenous fistula24.03.03.0010.000245%-
Atrial fibrillation02.03.03.0020.018251%
Atrial flutter02.03.03.0030.002569%
Atrial tachycardia02.03.03.0040.000245%
Atrioventricular block complete02.03.01.0030.001468%
Barrett's oesophagus07.11.03.0020.000245%-
Benign prostatic hyperplasia21.04.02.0010.000367%-
Bile duct stone09.02.02.0030.000856%-
Bladder diverticulum20.03.01.0090.000783%-
Bladder neoplasm16.08.03.002; 20.03.04.0020.000367%-
Blindness transient06.02.10.006; 17.17.01.0040.000905%-
Blindness unilateral06.02.10.007; 17.17.01.0160.001639%-
Brain compression17.07.02.0050.000489%-
Brain stem haemorrhage17.08.01.031; 24.07.04.0150.000489%-
Brain stem infarction17.08.01.024; 24.04.06.0140.000489%-
Calculus bladder20.04.03.0010.000245%-
Cardiac arrest02.03.04.0010.012844%
Cardiac failure02.05.01.0010.025200%
Cardiac failure acute02.05.01.0050.001346%-
Cardiac failure congestive02.05.01.0020.008196%-
Cardiac tamponade02.06.01.0010.025934%
Cardiogenic shock02.05.01.003; 24.06.02.0060.004893%-
Carotid artery stenosis17.08.02.001; 24.04.06.0010.002006%-
Carotid artery thrombosis17.08.01.025; 24.01.04.0070.000734%-
Cerebellar infarction17.08.01.013; 24.04.06.0070.001468%-
Cerebral artery embolism17.08.01.001; 24.01.04.0010.004330%-
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