Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Barrett's oesophagus
ADR ID BADD_A00424
ADR Hierarchy
07      Gastrointestinal disorders
07.11      Gastrointestinal conditions NEC
07.11.03      Gastrointestinal mucosal dystrophies and secretion disorders
07.11.03.002      Barrett's oesophagus
Description A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett's columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus. [MeSH]
MedDRA Code 10004137
MeSH ID D001471
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Barrett's esophagus | Barrett's oesophagitis | Barrett's oesophagitis with dysplasia | Barrett's oesophagus | Pre-malignant changes to oesophagus | Premalignant changes to esophagus | Endobrachyoesophagus | Pre-malignant changes to esophagus | Endobrachyooesophagus | Barrett's esophagitis with dysplasia | Oesophageal intestinal metaplasia | Esophageal intestinal metaplasia | Premalignant changes to oesophagus | Barrett's esophagitis | Oesophageal gastric cardia type metaplasia | Esophageal gastric cardia type metaplasia | Oesophageal irregular z-line | Esophageal irregular z-line | Oesophageal elevated z-line | Esophageal elevated z-line | Barrett's esophagus high grade dysplasia | Barrett's oesophagus high grade dysplasia | Short-segment Barrett's esophagus | Long-segment Barrett's esophagus | Long-segment Barrett's oesophagus | Short-segment Barrett's oesophagus | Barrett Esophagus | Barrett Metaplasia | Barrett Metaplasias | Metaplasia, Barrett | Metaplasias, Barrett | Barrett's Syndrome | Barretts Syndrome | Barrett Syndrome | Barrett's Esophagus | Barretts Esophagus | Esophagus, Barrett's | Esophagus, Barrett | Barrett Epithelium | Epithelium, Barrett
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000198%
BADD_D00151Apixaban0.000108%
BADD_D00563Dabigatran0.000245%
BADD_D00628Dexlansoprazole--
BADD_D00680Dimethyl fumarate0.001080%
BADD_D00815Esomeprazole--
BADD_D00816Esomeprazole magnesium--
BADD_D00817Esomeprazole sodium--
BADD_D00818Esomeprazole strontium--
BADD_D00898Finasteride0.000135%
BADD_D01096Hydromorphone--
BADD_D01245Lansoprazole0.000199%
BADD_D01374Meloxicam0.000063%
BADD_D01567Nilotinib0.000168%
BADD_D01602Olmesartan0.001070%
BADD_D01668Pantoprazole0.000044%
BADD_D01834Prednisone0.000013%
BADD_D01835Pregabalin0.000052%
BADD_D01913Ranitidine0.000150%
BADD_D01954Rivaroxaban0.000127%
BADD_D02029Sitagliptin0.000053%
BADD_D02047Sodium oxybate0.000671%
BADD_D02373Warfarin0.000042%
BADD_D02507Deutetrabenazine0.001830%
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