Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Brain stem infarction
ADR ID BADD_A00670
ADR Hierarchy
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.06      Cerebrovascular and spinal necrosis and vascular insufficiency
24.04.06.014      Brain stem infarction
17      Nervous system disorders
17.08      Central nervous system vascular disorders
17.08.01      Central nervous system haemorrhages and cerebrovascular accidents
17.08.01.024      Brain stem infarction
Description Infarctions that occur in the BRAIN STEM which is comprised of the MIDBRAIN; PONS; and MEDULLA OBLONGATA. There are several named syndromes characterized by their distinctive clinical manifestations and specific sites of ischemic injury. [MeSH]
MedDRA Code 10006147
MeSH ID D020526
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Brain stem infarction | Pontine infarction | Brain Stem Infarctions | Brain Stem Infarction | Infarction, Brain Stem | Brainstem Stroke | Stroke, Brainstem | Infarctions, Brainstem | Brainstem Infarctions | Brainstem Infarction | Infarction, Brainstem | Infarctions, Brain Stem | Claude Syndrome | Weber Syndrome | Millard-Gublar Syndrome | Millard Gublar Syndrome | Syndrome, Millard-Gublar | Top of the Basilar Syndrome | Benedict Syndrome | Foville Syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00151Apixaban0.000130%
BADD_D00193Axitinib0.000112%
BADD_D00349Capecitabine0.000112%
BADD_D00563Dabigatran0.000489%
BADD_D00623Dexamethasone0.000218%
BADD_D00775Enzalutamide0.000334%
BADD_D00821Estradiol0.000031%
BADD_D00978Fulvestrant0.000334%
BADD_D00979Furosemide0.000021%
BADD_D01119Ibrutinib0.000112%
BADD_D01281Levonorgestrel0.000473%
BADD_D01401Metformin0.000005%
BADD_D01470Minocycline0.000177%
BADD_D01567Nilotinib0.000224%
BADD_D01799Ponatinib0.000112%
BADD_D01822Prasugrel0.000384%
BADD_D01831Prednisolone0.000035%
BADD_D01954Rivaroxaban0.000475%
BADD_D02028Sirolimus0.000134%
BADD_D02150Temozolomide0.000112%
BADD_D02170Testosterone0.000227%
BADD_D02236Tofacitinib0.000241%
BADD_D02331Valsartan0.000053%
BADD_D02361Vincristine sulfate--
BADD_D02373Warfarin0.000056%
BADD_D02375Water--
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