Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Leiomyosarcoma
ADR ID BADD_A07352
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.09      Musculoskeletal and connective tissue neoplasms
15.09.03      Malignant musculoskeletal and connective tissue neoplasms
15.09.03.016      Leiomyosarcoma
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.33      Soft tissue neoplasms malignant and unspecified
16.33.07      Leiomyosarcomas
16.33.07.001      Leiomyosarcoma
Description A sarcoma containing large spindle cells of smooth muscle. Although it rarely occurs in soft tissue, it is common in the viscera. It is the most common soft tissue sarcoma of the gastrointestinal tract and uterus. The median age of patients is 60 years. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1865) [MeSH]
MedDRA Code 10024189
MeSH ID D007890
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Leiomyosarcoma | Leiomyosarcoma non-metastatic | Leiomyosarcoma NOS | Leiomyosarcomas | Leiomyosarcoma, Epithelioid | Epithelioid Leiomyosarcoma | Epithelioid Leiomyosarcomas | Leiomyosarcomas, Epithelioid | Leiomyosarcoma, Myxoid | Leiomyosarcomas, Myxoid | Myxoid Leiomyosarcoma | Myxoid Leiomyosarcomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00474Cisplatin0.000112%
BADD_D00723Doxorubicin0.000224%
BADD_D01136Imatinib0.000112%
BADD_D01281Levonorgestrel0.000473%
BADD_D01687Pazopanib0.000168%
BADD_D01835Pregabalin0.000052%
BADD_D01913Ranitidine0.000063%
BADD_D02165Teriflunomide0.000241%
BADD_D02253Trabectedin0.000112%
BADD_D02375Water--
BADD_D02464Fingolimod0.000362%
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