Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Leiomyosarcomas
ADR ID BADD_A07353
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.33      Soft tissue neoplasms malignant and unspecified
16.33.07      Leiomyosarcomas
Description A sarcoma containing large spindle cells of smooth muscle. Although it rarely occurs in soft tissue, it is common in the viscera. It is the most common soft tissue sarcoma of the gastrointestinal tract and uterus. The median age of patients is 60 years. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1865) [MeSH]
MedDRA Code 10024190
MeSH ID D007890
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Leiomyosarcoma | Leiomyosarcomas | Leiomyosarcoma, Epithelioid | Epithelioid Leiomyosarcoma | Epithelioid Leiomyosarcomas | Leiomyosarcomas, Epithelioid | Leiomyosarcoma, Myxoid | Leiomyosarcomas, Myxoid | Myxoid Leiomyosarcoma | Myxoid Leiomyosarcomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00474Cisplatin0.000112%
BADD_D00680Dimethyl fumarate0.000800%
BADD_D00723Doxorubicin0.000728%
BADD_D01136Imatinib0.000112%
BADD_D01281Levonorgestrel0.000473%
BADD_D01687Pazopanib0.000504%
BADD_D01835Pregabalin0.000052%
BADD_D01913Ranitidine0.000063%
BADD_D02165Teriflunomide0.000241%
BADD_D02253Trabectedin0.000280%
BADD_D02375Water--
BADD_D02453Midostaurin--
BADD_D02464Fingolimod0.000362%
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