Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Multiple organ dysfunction syndrome
ADR ID BADD_A06819
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.03      General signs and symptoms NEC
08.01.03.057      Multiple organ dysfunction syndrome
Description A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative. [MeSH]
MedDRA Code 10077361
MeSH ID D009102
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
MOF | Multi organ failure | Multi-organ failure | Multiorgan failure | Multiple organ failure | Multiple organ dysfunction syndrome | Multiple Organ Failure | Multiple Organ Dysfunction Syndrome | Organ Failure, Multiple | Failure, Multiple Organ | Multiple Organ Failures | MODS | Organ Dysfunction Syndrome, Multiple
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01258Leucovorin0.001239%
BADD_D01265Levetiracetam0.002305%
BADD_D01275Levofloxacin0.000358%
BADD_D01285Levothyroxine--
BADD_D01295Linezolid0.009056%
BADD_D01303Lithium carbonate0.000535%
BADD_D01304Lithium cation0.000480%
BADD_D01336Macitentan0.002010%
BADD_D01376Melphalan0.000168%
BADD_D01378Memantine0.000121%
BADD_D01392Mercaptopurine0.001041%
BADD_D01393Meropenem0.000267%
BADD_D01401Metformin0.000785%
BADD_D01405Methadone0.001724%
BADD_D01414Methimazole0.000708%
BADD_D01418Methotrexate--
BADD_D01420Methoxsalen0.000521%
BADD_D01433Methylprednisolone0.000160%
BADD_D01442Metoclopramide0.000686%
BADD_D01455Micafungin0.000374%
BADD_D01465Miglustat0.004312%
BADD_D01470Minocycline0.001830%
BADD_D01498Morphine0.001281%
BADD_D01502Moxifloxacin hydrochloride--
BADD_D01508Mycophenolic acid0.001427%
BADD_D01512Nadolol0.000517%
BADD_D01566Nifedipine0.000075%
BADD_D01567Nilotinib0.000951%
BADD_D01574Nitric oxide-
BADD_D01576Nitrofurantoin--
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