Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Brain injury
ADR ID BADD_A06477
ADR Hierarchy
17      Nervous system disorders
17.11      Structural brain disorders
17.11.01      Structural brain disorders NEC
17.11.01.003      Brain injury
19      Psychiatric disorders
19.07      Psychiatric disorders NEC
19.07.03      Mental disorders due to a general medical condition NEC
19.07.03.007      Brain injury
Description Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits. [MeSH]
MedDRA Code 10067967
MeSH ID D001930; D002534
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Anoxic brain damage | Brain damage (excl perinatal) | Hypoxic brain damage | Cerebral damage | Brain damage | Brain injury | Brain Injuries | Injuries, Brain | Brain Injury | Injury, Brain | Injuries, Acute Brain | Acute Brain Injuries | Acute Brain Injury | Brain Injury, Acute | Injury, Acute Brain | Brain Injuries, Acute | Brain Lacerations | Brain Laceration | Laceration, Brain | Lacerations, Brain | Brain Injuries, Focal | Brain Injury, Focal | Focal Brain Injury | Injuries, Focal Brain | Injury, Focal Brain | Focal Brain Injuries
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01971Rosuvastatin--
BADD_D02010Sertraline0.000057%
BADD_D02018Sildenafil0.000215%
BADD_D02047Sodium oxybate0.000805%
BADD_D02084Sugammadex0.001239%
BADD_D02098Sumatriptan--
BADD_D02105Tacrolimus0.000891%
BADD_D02106Tadalafil0.000195%
BADD_D02150Temozolomide0.000448%
BADD_D02170Testosterone0.000364%
BADD_D02171Testosterone cypionate0.005242%
BADD_D02195Theophylline--
BADD_D02209Thyrotropin releasing hormone--
BADD_D02246Tolvaptan0.000087%
BADD_D02247Topiramate0.000151%
BADD_D02268Treprostinil0.000164%
BADD_D02281Trifluoperazine--
BADD_D02331Valsartan0.000079%
BADD_D02337Varenicline0.000681%
BADD_D02341Vecuronium bromide0.000057%
BADD_D02348Verapamil0.000148%
BADD_D02369Voriconazole0.005809%
BADD_D02373Warfarin0.000098%
BADD_D02375Water--
BADD_D02428Loperamide0.000507%
BADD_D02452Icatibant-
BADD_D02464Fingolimod0.001808%
BADD_D02471Oxygen0.001239%
BADD_D02473Sodium chloride--
BADD_D02588Remdesivir0.000423%
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ADReCS-Target
ADR Term Drug Name Target