Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Testosterone cypionate
Drug ID BADD_D02171
Description Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester. Its benefit compared to other testosterone derivatives is the slow rate of release after injection and longer half-life. It was developed by the company Pharmacia and Upjohn and FDA approved on July 25, 1979.
Indications and Usage Testosterone cypionate is used in males that present conditions derived from a deficiency or absence of endogenous testosterone. These conditions are 1) primary hypogonadism, defined as the testicular failure due to cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome or orchidectomy; and 2) hypogonadotropic hypogonadism characterized by idiopathic gonadotropin, LHRH deficiency or pituitary-hypothalamic injury from tumors, trauma or radiation.[L1153]
Marketing Status Prescription; Discontinued
ATC Code G03BA03
DrugBank ID DB13943
KEGG ID D00957
MeSH ID C016131
PubChem ID 441404
TTD Drug ID Not Available
NDC Product Code 62756-016; 0574-0820; 69097-536; 76420-065; 46439-8736; 48087-0096; 0409-6562; 71205-289; 51927-2706; 0009-0086; 0143-9659; 50090-0330; 51552-0104; 0009-0417; 0009-0347; 0143-9726; 0591-4128; 0409-6557; 72833-678; 60870-0252; 69097-802; 50090-4147; 62991-3132; 0517-1830; 64025-0021; 62756-017; 0143-9005; 52536-625; 51927-0189; 65089-0049; 50090-4920; 0009-0027; 63629-8705; 0574-0827; 50090-4921; 69097-537; 43647-678; 63187-647; 0009-0085; 50090-4446; 38779-0164; 63275-9982; 63629-8706; 82393-114; 46204-0371; 49803-006; 62756-015; 49452-7660; 0395-8137; 22552-0010
Synonyms testosterone 17 beta-cypionate | testosterone cypionate | testosterone 17 beta-cyclopentanepropionate | testosterone 17 beta-cyclopentylpropionate | Depo-Testosterone | Depo-Testosterone Cypionate | deposteron | Duratest | Testa-C | Testex Elmu | Andronate | Depostomead
Chemical Information
Molecular Formula C27H40O3
CAS Registry Number 58-20-8
SMILES CC12CCC3C(C1CCC2OC(=O)CCC4CCCC4)CCC5=CC(=O)CCC35C
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain upper07.01.05.003--
Acne23.02.01.0010.001913%Not Available
Acute myocardial infarction02.02.02.001; 24.04.04.0010.016264%Not Available
Alopecia23.02.02.001--
Amnesia17.03.02.001; 19.20.01.0010.003348%
Anaphylactoid reaction10.01.07.003; 24.06.03.007--Not Available
Anger19.04.02.0010.001435%Not Available
Angina pectoris02.02.02.002; 24.04.04.0020.003348%
Angina unstable02.02.02.004; 24.04.04.0040.000957%Not Available
Anxiety19.06.02.0020.005262%
Aphasia17.02.03.001; 19.21.01.0010.000957%
Arrhythmia02.03.02.0010.000250%Not Available
Arteriosclerosis coronary artery02.02.01.011; 24.04.04.0120.000250%Not Available
Arthralgia15.01.02.001--
Arthropathy15.01.01.0030.000957%Not Available
Asthenia08.01.01.0010.005740%Not Available
Atrial fibrillation02.03.03.0020.004305%
Atrial flutter02.03.03.0030.001435%
Azoospermia21.03.03.001--
Back pain15.03.04.005--
Blindness06.02.02.001; 17.17.01.0030.002392%Not Available
Blindness unilateral06.02.02.009; 17.17.01.0160.000957%Not Available
Blood calcium13.11.01.041--Not Available
Blood calcium decreased13.11.01.002--Not Available
Blood chloride13.11.01.042--Not Available
Blood glucose increased13.02.02.0020.000957%Not Available
Blood phosphorus13.11.01.023--Not Available
Blood potassium13.11.01.032--Not Available
Blood potassium abnormal13.11.01.024--Not Available
Blood testosterone decreased13.10.05.0040.003348%Not Available
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