Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Metastasis
ADR ID BADD_A06072
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.22      Metastases
16.22.01      Metastases to unknown and unspecified sites
16.22.01.001      Metastasis
Description The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. [MeSH]
MedDRA Code 10062194
MeSH ID D009362
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Metastases NOS | Secondary carcinoma | Secondary carcinoma (known primary) | Secondary malignant neoplasm of other specified site | Secondary malignant neoplasm of other specified site, not elsewhere classified | Secondary malignant neoplasm of other specified sites | Secondary malignant neoplasm of respiratory and digestive systems | Metastasis | Synchronous metastases | Metachronous metastasis | Neoplasm Metastasis | Metastases, Neoplasm | Neoplasm Metastases | Metastases | Metastasis, Neoplasm
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00014Abiraterone0.002402%
BADD_D00047Afatinib0.000672%
BADD_D00142Anastrozole0.000556%
BADD_D00193Axitinib0.000381%
BADD_D00194Azacitidine0.000112%
BADD_D00230Bendamustine--
BADD_D00271Bicalutamide0.007733%
BADD_D00285Bosentan0.000181%
BADD_D00330Cabozantinib0.000168%
BADD_D00349Capecitabine0.000895%
BADD_D00364Carboplatin0.000448%
BADD_D00367Carfilzomib0.000112%
BADD_D00414Ceritinib0.000224%
BADD_D00474Cisplatin0.000168%
BADD_D00511Clozapine--
BADD_D00535Crizotinib0.000246%
BADD_D00566Dabrafenib0.000112%
BADD_D00599Degarelix--
BADD_D00723Doxorubicin0.000112%
BADD_D00775Enzalutamide0.001168%
BADD_D00800Erlotinib0.001981%
BADD_D00858Everolimus0.002553%
BADD_D00879Fentanyl0.000211%
BADD_D00898Finasteride0.000045%
BADD_D00931Fluorouracil0.000368%
BADD_D00943Flutamide--
BADD_D00978Fulvestrant0.002336%
BADD_D00979Furosemide0.000021%
BADD_D01008Gefitinib0.000336%
BADD_D01009Gemcitabine0.000224%
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