Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Diabetic nephropathy
ADR ID BADD_A05995
ADR Hierarchy
20      Renal and urinary disorders
20.05      Nephropathies
20.05.03      Nephropathies and tubular disorders NEC
20.05.03.011      Diabetic nephropathy
05      Endocrine disorders
05.07      Diabetic complications
05.07.02      Diabetic complications renal
05.07.02.003      Diabetic nephropathy
14      Metabolism and nutrition disorders
14.07      Diabetic complications
14.07.02      Diabetic complications renal
14.07.02.003      Diabetic nephropathy
Description KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE. [MeSH]
MedDRA Code 10061835
MeSH ID D003928
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Diabetes with renal manifestations | Diabetic nephropathy NOS | Diabetic renal disease | Type I diabetes mellitus with renal manifestations | Type II diabetes mellitus with renal manifestations | Diabetic nephropathy | Diabetic kidney disease | Diabetic Nephropathies | Nephropathies, Diabetic | Nephropathy, Diabetic | Diabetic Nephropathy | Diabetic Kidney Disease | Diabetic Kidney Diseases | Kidney Disease, Diabetic | Kidney Diseases, Diabetic | Diabetic Glomerulosclerosis | Kimmelstiel-Wilson Syndrome | Kimmelstiel Wilson Syndrome | Syndrome, Kimmelstiel-Wilson | Kimmelstiel-Wilson Disease | Kimmelstiel Wilson Disease | Nodular Glomerulosclerosis | Glomerulosclerosis, Nodular | Glomerulosclerosis, Diabetic | Intracapillary Glomerulosclerosis
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00033Acetylsalicylic acid0.000022%
BADD_D00044Adefovir dipivoxil0.000282%
BADD_D00073Aliskiren0.001828%
BADD_D00165Aripiprazole0.000079%
BADD_D00193Axitinib0.000112%
BADD_D00347Candesartan cilexetil--
BADD_D00578Dapagliflozin0.000219%
BADD_D00765Empagliflozin--
BADD_D00979Furosemide0.000014%
BADD_D01245Lansoprazole0.000249%
BADD_D01401Metformin0.000027%
BADD_D01835Pregabalin0.000078%
BADD_D02029Sitagliptin0.000053%
BADD_D02105Tacrolimus0.001188%
BADD_D02154Tenofovir0.001939%
BADD_D02236Tofacitinib0.000241%
BADD_D02375Water--
BADD_D02392Zoledronic acid0.004294%
BADD_D02436Atorvastatin0.000020%
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