Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Nuchal rigidity
ADR ID BADD_A05585
ADR Hierarchy
17      Nervous system disorders
17.05      Neuromuscular disorders
17.05.02      Muscle tone abnormal
17.05.02.006      Nuchal rigidity
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.04      Muscle tone abnormalities
15.05.04.005      Nuchal rigidity
Description Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73) [MeSH]
MedDRA Code 10058483
MeSH ID D009127
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Neck rigid | Neck rigidity | Rigidity neck | Nuchal rigidity | Muscle Rigidity | Rigidity, Muscle | Rigidity, Muscular | Muscular Rigidity | Cogwheel Rigidity | Cogwheel Rigidities | Rigidities, Cogwheel | Rigidity, Cogwheel | Nuchal Rigidity | Rigidity, Nuchal | Extrapyramidal Rigidity | Rigidity, Extrapyramidal | Gegenhalten | Gegenhaltens | Catatonic Rigidity | Rigidity, Catatonic | Extensor Rigidity | Rigidity, Extensor
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01679Paroxetine--
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01682Paroxetine impurity a--
BADD_D01683Paroxetine mesylate--
BADD_D01761Phenylcyclopropan-1-amine;sulfuric acid--
BADD_D01771Pilocarpine hydrochloride--
BADD_D01774Pimozide--
BADD_D01795Polymyxin b sulfate--
BADD_D01804Posaconazole--
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01834Prednisone0.000013%
BADD_D01835Pregabalin--
BADD_D01858Propagermanium--
BADD_D01864Propofol--
BADD_D01888Quetiapine--
BADD_D01889Quetiapine fumarate--
BADD_D01898Rabeprazole--
BADD_D01919Reboxetine--
BADD_D01951Risperidone--
BADD_D01952Ritonavir--
BADD_D02002Selegiline--
BADD_D02192Thalidomide--
BADD_D02210Tiagabine--
BADD_D02236Tofacitinib0.000530%
BADD_D02254Tramadol--
BADD_D02325Valdecoxib--
BADD_D02329Valproic acid--
BADD_D02346Venlafaxine--
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