Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Tympanic membrane perforation
ADR ID BADD_A04405
ADR Hierarchy
04      Ear and labyrinth disorders
04.05      Middle ear disorders (excl congenital)
04.05.04      Tympanic membrane disorders (excl infections)
04.05.04.001      Tympanic membrane perforation
12      Injury, poisoning and procedural complications
12.01      Injuries NEC
12.01.14      Ear injuries NEC
12.01.14.001      Tympanic membrane perforation
Description A temporary or persistent opening in the eardrum (TYMPANIC MEMBRANE). Clinical signs depend on the size, location, and associated pathological condition. [MeSH]
MedDRA Code 10045210
MeSH ID D018058
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Attic perforation of tympanic membrane | Attic perforation of tympanum | Central perforation of tympanic membrane | Central perforation of tympanum | Ear drum perforation | Marginal perforation of tympanum | Multiple perforations of tympanic membrane | Open wound of ear drum, complicated | Open wound of ear drum, uncomplicated | Other marginal perforation of tympanic membrane | Perforated eardrum | Perforation of tympanic membrane | Perforation of tympanic membrane, unspecified | Total perforation of tympanic membrane | Trauma ear drum | Tympanic membrane perforation | Tympanic Membrane Perforation | Membrane Perforation, Tympanic | Eardrum Perforation | Perforation, Eardrum | Tympanic Membrane Rupture | Membrane Rupture, Tympanic | Rupture, Tympanic Membrane
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000132%
BADD_D00260Betamethasone--
BADD_D00436Chlorhexidine gluconate--
BADD_D00474Cisplatin0.000246%
BADD_D00480Clarithromycin--
BADD_D00623Dexamethasone0.000756%
BADD_D00720Doxepin--
BADD_D00809Escitalopram--
BADD_D00924Fluocinolone acetonide--
BADD_D00932Fluoxetine0.000020%
BADD_D00981Gabapentin--
BADD_D01119Ibrutinib0.000112%
BADD_D01209Isosorbide--
BADD_D01211Isosorbide mononitrate--
BADD_D01253Lenalidomide0.002604%
BADD_D01336Macitentan0.000265%
BADD_D01418Methotrexate--
BADD_D01798Pomalidomide0.000241%
BADD_D01933Ribavirin0.005934%
BADD_D01937Rifapentine--
BADD_D01978Ruxolitinib0.000700%
BADD_D02236Tofacitinib0.001302%
BADD_D02272Triamcinolone acetonide0.000027%
BADD_D02329Valproic acid0.000150%
The 1th Page    1    Total 1 Pages