Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Transplant rejection
ADR ID BADD_A04375
ADR Hierarchy
10      Immune system disorders
10.02      Immune disorders NEC
10.02.03      Transplant rejections
10.02.03.002      Transplant rejection
12      Injury, poisoning and procedural complications
12.02      Procedural related injuries and complications NEC
12.02.05      Non-site specific procedural complications
12.02.05.022      Transplant rejection
Description An immune response with both cellular and humoral components, directed against an allogeneic transplant, whose tissue antigens are not compatible with those of the recipient. [MeSH]
MedDRA Code 10044439
MeSH ID D006084
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Graft rejection | Transplant rejection | Vascular graft rejection | Acute cellular rejection | Chronic cellular rejection | Graft rejection episode | Humoral rejection | Antibody-mediated rejection | Acute allograft rejection | Acute graft rejection | Hyperacute allograft rejection | Chronic antibody-mediated rejection | Graft Rejection | Graft Rejections | Rejection, Graft | Rejections, Graft | Transplant Rejection | Transplantation Rejection | Rejection, Transplantation | Rejections, Transplantation | Transplantation Rejections | Rejection, Transplant | Rejections, Transplant | Transplant Rejections
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00194Azacitidine0.000112%
BADD_D00195Azathioprine0.000313%
BADD_D00284Bortezomib0.000112%
BADD_D00551Cyclosporine0.001326%
BADD_D00858Everolimus0.000535%
BADD_D01003Ganciclovir--
BADD_D01167Interferon alfa-2b--
BADD_D01322Losartan0.000010%
BADD_D01433Methylprednisolone0.000160%
BADD_D01508Mycophenolic acid0.003329%
BADD_D01567Nilotinib--
BADD_D01804Posaconazole--
BADD_D01831Prednisolone0.000140%
BADD_D01832Prednisolone acetate0.014032%
BADD_D01834Prednisone0.000058%
BADD_D01933Ribavirin0.023735%
BADD_D01978Ruxolitinib0.000137%
BADD_D02006Selexipag0.000082%
BADD_D02028Sirolimus0.001206%
BADD_D02105Tacrolimus0.025961%
BADD_D02326Valganciclovir--
BADD_D02327Valganciclovir hydrochloride--
BADD_D02369Voriconazole0.005809%
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