Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Valganciclovir hydrochloride
Drug ID BADD_D02327
Description Valganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections. As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
Indications and Usage Valganciclovir is an antiviral medication used for the treatment of cytomegalovirus infections.
Marketing Status approved; investigational
ATC Code J05AB14
DrugBank ID DB01610
KEGG ID D03256
MeSH ID D000077562
PubChem ID 135413534
TTD Drug ID D06GWF
NDC Product Code 12869-038; 55111-884; 63739-357; 0603-6330; 55111-929; 61876-0072; 27241-159; 64380-153; 17337-0040; 63310-2410; 65015-798; 65977-0070; 65015-818; 31722-837; 43598-356; 61269-485; 72205-019; 69875-8044; 0591-2579; 65862-756; 0004-0039; 63629-2288; 65862-753; 63285-852; 71666-008
UNII 4P3T9QF9NZ
Synonyms Valganciclovir | Ganciclovir L-valyl Ester | Ganciclovir L valyl Ester | Valcyt | Valganciclovir Hydrochloride | Valcyte
Chemical Information
Molecular Formula C14H23ClN6O5
CAS Registry Number 175865-59-5
SMILES CC(C)C(C(=O)OCC(CO)OCN1C=NC2=C1N=C(NC2=O)N)N.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Acne23.02.01.001---
Agitation17.02.05.012; 19.06.02.001--
Anaemia01.03.02.001--
Aplastic anaemia01.03.03.002---
Arthralgia15.01.02.001--
Ascites02.05.04.002; 07.07.01.001; 09.01.05.003--
Asthenia08.01.01.001---
Back pain15.03.04.005--
Blood creatine increased13.13.01.001---
Carnitine decreased13.12.02.003---
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Cough22.02.03.001--
Dehydration14.05.05.001--
Depression19.15.01.001--
Dermatitis23.03.04.002---
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dyspepsia07.01.02.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Dysuria20.02.02.002--
Fatigue08.01.01.002--
Hallucination19.10.04.003--
Headache17.14.01.001--
Hepatic function abnormal09.01.02.001---
Hyperglycaemia05.06.02.002; 14.06.02.002--
Hyperkalaemia14.05.03.001--
Hypersensitivity10.01.03.003--
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