Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Tooth discolouration
ADR ID BADD_A04338
ADR Hierarchy
07      Gastrointestinal disorders
07.09      Dental and gingival conditions
07.09.02      Dental surface disorders
07.09.02.001      Tooth discolouration
Description Any change in the hue, color, or translucency of a tooth due to any cause. Restorative filling materials, drugs (both topical and systemic), pulpal necrosis, or hemorrhage may be responsible. (Jablonski, Dictionary of Dentistry, 1992, p253) [MeSH]
MedDRA Code 10044032
MeSH ID D014075
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Discoloration tooth | Enamel mottling | Fluorescence tooth | Mottled teeth | Mottling enamel | Posteruptive color changes of teeth | Posteruptive colour changes of teeth | Stain tooth | Teeth mottled | Teeth mottling | Teeth stained | Teeth staining | Teeth yellow | Tooth coloured yellow | Tooth discoloration | Tooth discolouration | Tooth colored yellow | Discolouration tooth | Post eruptive colour changes of teeth | Post eruptive color changes of teeth | Tooth discolouration blue | Tooth discoloration blue | Tooth Discoloration | Discoloration, Tooth | Discolorations, Tooth | Tooth Discolorations
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000172%
BADD_D00103Amikacin0.000329%
BADD_D00129Amoxicillin--
BADD_D00172Asenapine0.004823%
BADD_D00343Californium-249 oxide--
BADD_D00356Carbamazepine--
BADD_D00378Cefaclor--
BADD_D00397Cefprozil--
BADD_D00412Cephalexin--
BADD_D00436Chlorhexidine gluconate--
BADD_D00451Cholestyramine--
BADD_D00471Ciprofloxacin--
BADD_D00480Clarithromycin--
BADD_D00605Demeclocycline--
BADD_D00606Demeclocycline hydrochloride--
BADD_D00725Doxycycline--
BADD_D00802Ertapenem0.000379%
BADD_D00804Erythromycin--
BADD_D00858Everolimus0.000520%
BADD_D00883Ferric oxyhydroxide-
BADD_D00945Fluticasone--
BADD_D00947Fluticasone propionate--
BADD_D00981Gabapentin--
BADD_D01213Isotretinoin0.000695%
BADD_D01265Levetiracetam0.000119%
BADD_D01295Linezolid0.026510%
BADD_D01470Minocycline0.002243%
BADD_D01471Minocycline anion--
BADD_D01472Minocycline hydrochloride--
BADD_D01498Morphine--
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