Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Rhabdomyolysis
ADR ID BADD_A03877
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.05      Myopathies
15.05.05.002      Rhabdomyolysis
Description A disorder characterized by the breakdown of muscle tissue resulting in the release of muscle fiber contents into the bloodstream. [CTCAE] Necrosis or disintegration of skeletal muscle often followed by myoglobinuria. [MeSH]
MedDRA Code 10039020
MeSH ID D012206
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Muscle dissolution | Rhabdomyolysis | Rhabdomyolyses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01971Rosuvastatin0.001589%
BADD_D01972Rosuvastatin calcium--
BADD_D01989Saquinavir mesylate--
BADD_D02010Sertraline0.000363%
BADD_D02015Sevoflurane0.000447%
BADD_D02026Simvastatin0.001267%
BADD_D02028Sirolimus0.001474%
BADD_D02029Sitagliptin0.000955%
BADD_D02034Sodium bicarbonate0.000641%
BADD_D02058Sorafenib--
BADD_D02060Sotalol0.000281%
BADD_D02062Sparfloxacin--
BADD_D02066Spironolactone0.000110%
BADD_D02079Succinylcholine0.000154%
BADD_D02080Succinylcholine chloride--
BADD_D02091Sulfamethoxazole--
BADD_D02093Sulfasalazine--
BADD_D02100Sunitinib--
BADD_D02101Sunitinib malate--
BADD_D02105Tacrolimus--
BADD_D02145Telbivudine--
BADD_D02147Telmisartan0.000781%
BADD_D02151Temsirolimus--
BADD_D02154Tenofovir--
BADD_D02155Tenofovir disoproxil--
BADD_D02156Tenofovir disoproxil fumarate--
BADD_D02160Terbinafine0.001415%
BADD_D02161Terbinafine hydrochloride--
BADD_D02172Testosterone enanthate-
BADD_D02175Tetrabenazine0.000808%
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ADReCS-Target
ADR Term Drug Name Target