Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Retinal degeneration
ADR ID BADD_A03842
ADR Hierarchy
06      Eye disorders
06.09      Ocular structural change, deposit and degeneration NEC
06.09.03      Retinal structural change, deposit and degeneration
06.09.03.002      Retinal degeneration
Description A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304) [MeSH]
MedDRA Code 10038845
MeSH ID D012162; D000793; D012162
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Angioid streaks of choroid | Chorioretinal atrophy | Choroidal degeneration, unspecified | Choroidal degenerations | Degeneration retinal | Diffuse secondary atrophy of choroid | Lattice degeneration of retina | Microcystoid degeneration of retina | Ocular fundus pigment epithelium degeneration | Paving stone degeneration of retina | Peripheral retinal degeneration, unspecified | Peripheral retinal degenerations | Retinal atrophy | Retinal degeneration | Retinal pigment degeneration | Secondary pigmentary degeneration of retina | Secondary vitreoretinal degenerations | Senile atrophy of choroid | Senile reticular degeneration of retina | Retinal pigment clumping | Retinal gliosis | Angioid streaks | Peripapillary atrophy | Peripapillary crescent | Myopic crescent | Myopic conus | Chorioretinal degeneration | Retinal thinning | Loss of retinal thickness | Cobblestone degeneration | Retinal pigment epithelium granularity | Retinal Degeneration | Degeneration, Retinal | Degenerations, Retinal | Retinal Degenerations
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000066%
BADD_D00407Cefuroxime0.000286%
BADD_D00596Deferoxamine--
BADD_D00623Dexamethasone0.000145%
BADD_D00653Diclofenac0.000051%
BADD_D00661Didanosine--
BADD_D00924Fluocinolone acetonide0.003004%
BADD_D00981Gabapentin--
BADD_D01103Hydroxychloroquine0.002789%
BADD_D01104Hydroxychloroquine sulfate--
BADD_D01245Lansoprazole--
BADD_D01265Levetiracetam0.000079%
BADD_D01376Melphalan0.000560%
BADD_D01478Mitomycin0.000112%
BADD_D01594Ocriplasmin--
BADD_D01831Prednisolone0.000035%
BADD_D01835Pregabalin0.000078%
BADD_D01895Quinine0.002202%
BADD_D01898Rabeprazole--
BADD_D01912Ranibizumab--
BADD_D01916Rasagiline mesylate--
BADD_D02105Tacrolimus0.001040%
BADD_D02272Triamcinolone acetonide0.000096%
BADD_D02355Vigabatrin0.000249%
BADD_D02464Fingolimod0.000723%
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