Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Palmar-plantar erythrodysaesthesia syndrome
ADR ID BADD_A03260
ADR Hierarchy
23      Skin and subcutaneous tissue disorders
23.03      Epidermal and dermal conditions
23.03.05      Dermatitis ascribed to specific agent
23.03.05.009      Palmar-plantar erythrodysaesthesia syndrome
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.07      Sensory abnormalities NEC
17.02.07.009      Palmar-plantar erythrodysaesthesia syndrome
Description Not Available
MedDRA Code 10033553
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Hand and foot syndrome | Hand-and-foot syndrome | Palmar-plantar erythrodysaesth. | Palmar-plantar erythrodysaesthesia syndrome | Hand and foot syndrome secondary to chemotherapy | Palmar-plantar erythrodysesthesia syndrome | Palmar-plantar erythema | Hand and foot skin reaction | Acral erythema | Genital erythrodysesthesia | Genital erythrodysaesthesia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00036Acitretin0.001875%
BADD_D00047Afatinib0.001030%
BADD_D00048Aflibercept--
BADD_D00121Amlodipine--
BADD_D00193Axitinib0.018446%
BADD_D00330Cabozantinib0.088647%
BADD_D00331Cabozantinib s-malate--
BADD_D00349Capecitabine0.074891%
BADD_D00364Carboplatin0.001086%
BADD_D00422Cetuximab--
BADD_D00495Clofarabine0.000112%
BADD_D00549Cyclophosphamide--
BADD_D00560Cytarabine0.000504%
BADD_D00566Dabrafenib0.001477%
BADD_D00567Dabrafenib mesylate--
BADD_D00589Dasatinib--
BADD_D00593Decitabine0.000112%
BADD_D00699Docetaxel--
BADD_D00723Doxorubicin0.007398%
BADD_D00724Doxorubicin hydrochloride--
BADD_D00798Eribulin0.000392%
BADD_D00854Etoposide--
BADD_D00858Everolimus0.003318%
BADD_D00869Famotidine0.000168%
BADD_D00931Fluorouracil0.003787%
BADD_D00967Fosinopril--
BADD_D01009Gemcitabine0.000336%
BADD_D01127Idarubicin--
BADD_D01133Ifosfamide--
BADD_D01137Imatinib mesylate--
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ADReCS-Target
ADR Term Drug Name Target