Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Nephrotic syndrome
ADR ID BADD_A03027
ADR Hierarchy
20      Renal and urinary disorders
20.05      Nephropathies
20.05.01      Glomerulonephritis and nephrotic syndrome
20.05.01.002      Nephrotic syndrome
Description A disorder characterized by symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction. [CTCAE] Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA. [MeSH]
MedDRA Code 10029164
MeSH ID D009401; D009404
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Nephrosis | Nephrosis osmotic | Nephrotic syndrome | Nephrotic syndrome in diseases classified elsewhere | Nephrotic syndrome with lesion of membranoproliferative glomerulonephritis | Nephrotic syndrome with lesion of membranous glomerulonephritis | Nephrotic syndrome with lesion of minimal change glomerulonephritis | Nephrotic syndrome with lesion of proliferative glomerulonephritis | Nephrotic syndrome with other pathological lesion in kidney | Nephrotic syndrome with other specified pathological lesion in kidney | Nephrotic syndrome with unspecified pathological lesion in kidney | Syndrome nephrotic | Nephrotic syndrome worsened | Steroid-resistant nephrotic syndrome | Nephroses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01608Olsalazine sodium--
BADD_D01614Omeprazole--
BADD_D01624Orlistat0.005655%
BADD_D01629Osimertinib0.000168%
BADD_D01635Oxaprozin--
BADD_D01661Pamidronate disodium--
BADD_D01662Pamidronic acid0.000126%
BADD_D01668Pantoprazole0.000025%
BADD_D01672Paraldehyde--
BADD_D01687Pazopanib0.002418%
BADD_D01709Penicillamine0.000051%
BADD_D01735Pergolide--
BADD_D01736Pergolide mesylate--
BADD_D01756Phentermine0.000273%
BADD_D01765Phenytoin0.000191%
BADD_D01784Piroxicam--
BADD_D01831Prednisolone0.000419%
BADD_D01834Prednisone0.000072%
BADD_D01835Pregabalin0.000207%
BADD_D01841Probenecid--
BADD_D01856Propafenone--
BADD_D01857Propafenone hydrochloride--
BADD_D01900Rabies virus immune globulin (human)--
BADD_D01909Ramipril0.000140%
BADD_D01911Ramucirumab--
BADD_D01922Regorafenib0.000504%
BADD_D01933Ribavirin0.013845%
BADD_D01940Rilpivirine--
BADD_D01941Rilpivirine hydrochloride--
BADD_D01971Rosuvastatin0.000055%
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