Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00195Azathioprine--
BADD_D00198Azelastine--
BADD_D00199Azelastine hydrochloride--
BADD_D00200Azilsartan--
BADD_D00201Azilsartan kamedoxomil--
BADD_D00202Azilsartan medoxomil--
BADD_D00203Azithromycin--
BADD_D00204Azithromycin dihydrate--
BADD_D00205Azithromycin monohydrate--
BADD_D00207Bacillus calmette-guerin--
BADD_D00209Baclofen--
BADD_D00210Balsalazide--
BADD_D00211Balsalazide disodium--
BADD_D00214Basiliximab--
BADD_D00219Beclomethasone dipropionate--
BADD_D00225Belinostat0.000895%
BADD_D00227Benazepril--
BADD_D00228Benazepril hydrochloride--
BADD_D00229Benazeprilat--
BADD_D00230Bendamustine--
BADD_D00231Bendamustine hydrochloride--
BADD_D00244Benztropine0.000928%
BADD_D00258Betahistine--
BADD_D00263Betaxolol--
BADD_D00268Bevacizumab--
BADD_D00269Bexarotene0.000929%
BADD_D00271Bicalutamide--
BADD_D00277Bisoprolol0.014003%
BADD_D00278Bisoprolol fumarate--
BADD_D00282Blinatumomab--
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ADReCS-Target
ADR Term Drug Name Target