Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Dysarthria
ADR ID BADD_A01359
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.08      Speech and language abnormalities
17.02.08.001      Dysarthria
19      Psychiatric disorders
19.19      Communication disorders and disturbances
19.19.03      Speech articulation and rhythm disturbances
19.19.03.001      Dysarthria
Description A disorder characterized by slow and slurred speech resulting from an inability to coordinate the muscles used in speech. [CTCAE] Disorders of speech articulation caused by imperfect coordination of pharynx, larynx, tongue, or face muscles. This may result from CRANIAL NERVE DISEASES; NEUROMUSCULAR DISEASES; CEREBELLAR DISEASES; BASAL GANGLIA DISEASES; BRAIN STEM diseases; or diseases of the corticobulbar tracts (see PYRAMIDAL TRACTS). The cortical language centers are intact in this condition. (From Adams et al., Principles of Neurology, 6th ed, p489) [MeSH]
MedDRA Code 10013887
MeSH ID D004401
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Dysarthria | Inarticulateness | Slurred speech | Speech slurred | Articulation problem | Dysarthrophonia | Anarthria | Dysarthrias | Dysarthosis | Dysarthoses | Dysarthria, Spastic | Dysarthrias, Spastic | Spastic Dysarthria | Spastic Dysarthrias | Dysarthria, Mixed | Dysarthrias, Mixed | Mixed Dysarthria | Mixed Dysarthrias | Dysarthria, Scanning | Dysarthrias, Scanning | Scanning Dysarthria | Scanning Dysarthrias | Dysarthria, Flaccid | Dysarthrias, Flaccid | Flaccid Dysarthria | Flaccid Dysarthrias | Dysarthria, Guttural | Dysarthrias, Guttural | Guttural Dysarthria | Guttural Dysarthrias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01682Paroxetine impurity a--
BADD_D01683Paroxetine mesylate--
BADD_D01720Pentazocine lactate--
BADD_D01730Pentostatin--
BADD_D01733Perampanel0.000461%
BADD_D01743Perphenazine--
BADD_D01756Phentermine0.000164%
BADD_D01765Phenytoin0.004302%
BADD_D01766Phenytoin sodium--
BADD_D01808Potassium cation--
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01831Prednisolone0.000227%
BADD_D01834Prednisone0.000063%
BADD_D01835Pregabalin0.004450%
BADD_D01836Prilocaine--
BADD_D01846Procarbazine--
BADD_D01847Procarbazine hydrochloride--
BADD_D01848Prochlorperazine--
BADD_D01852Progesterone0.000125%
BADD_D01854Promethazine0.000181%
BADD_D01864Propofol0.000268%
BADD_D01876Pseudoephedrine--
BADD_D01881Pyridostigmine0.006800%
BADD_D01888Quetiapine0.000856%
BADD_D01889Quetiapine fumarate--
BADD_D01895Quinine0.001101%
BADD_D01909Ramipril0.001119%
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