Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00496Clofazimine--
BADD_D00497Clomiphene--
BADD_D00498Clomiphene citrate--
BADD_D00499Clomipramine--
BADD_D00500Clomipramine hydrochloride--
BADD_D00501Clonazepam--
BADD_D00502Clonidine--
BADD_D00503Clonidine hydrochloride--
BADD_D00504Clopidogrel--
BADD_D00511Clozapine0.216080%
BADD_D00516Codeine--
BADD_D00517Codeine sulfate--
BADD_D00519Colesevelam hydrochloride--
BADD_D00520Colestilan chloride--
BADD_D00521Colestipol--
BADD_D00522Colestipol hydrochloride--
BADD_D00526Conivaptan--
BADD_D00527Conivaptan hydrochloride--
BADD_D00531Corticotropin--
BADD_D00535Crizotinib0.018155%
BADD_D00536Crofelemer--
BADD_D00537Cromoglycate--
BADD_D00538Cromolyn--
BADD_D00543Cyclizine--
BADD_D00544Cyclo-upup--
BADD_D00545Cyclobenzaprine0.000032%
BADD_D00546Cyclobenzaprine hydrochloride--
BADD_D00549Cyclophosphamide--
BADD_D00551Cyclosporine--
BADD_D00552Cyproheptadine--
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