Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01439Methysergide--
BADD_D01442Metoclopramide--
BADD_D01444Metolazone--
BADD_D01445Metoprolol--
BADD_D01446Metoprolol succinate--
BADD_D01447Metoprolol tartrate--
BADD_D01449Metronidazole--
BADD_D01452Mexiletine--
BADD_D01453Mexiletine hydrochloride--
BADD_D01454Mianserin--
BADD_D01455Micafungin--
BADD_D01459Midazolam--
BADD_D01463Mifepristone--
BADD_D01464Miglitol--
BADD_D01465Miglustat0.015956%
BADD_D01466Milnacipran hydrochloride--
BADD_D01471Minocycline anion--
BADD_D01475Mirabegron0.009374%
BADD_D01476Mirtazapine--
BADD_D01477Misoprostol--
BADD_D01480Mitoxantrone--
BADD_D01481Mitoxantrone hydrochloride--
BADD_D01483Moclobemide--
BADD_D01484Modafinil--
BADD_D01485Moexipril hydrochloride--
BADD_D01486Moexiprilat--
BADD_D01487Molindone--
BADD_D01488Molindone hydrochloride--
BADD_D01498Morphine0.008744%
BADD_D01499Morphine sulfate--
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