Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Miglitol
Drug ID BADD_D01464
Description Miglitol inhibits the breakdown complex carbohydrates into glucose. It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing the digestion of carbohydrates (such as disaccharides, oligosaccharides, and polysaccharides) into monosaccharides which can be absorbed by the body. Miglitol should be taken at the start of a meal for maximal effect and the effect will depend on the amount of poly and oligosaccharides in the diet. Miglitol inhibits alpha-glucosidase, making less sugars available for digestion and reducing postprandial hyperglycemia. Unlike other drugs of the same class, miglitol is not metabolized and the unmetabolized drug is excreted by the kidneys.
Indications and Usage For use as an adjunct to diet to improve glycemic control in patients with non-insulin-dependent diabetes mellitus (NIDDM) whose hyperglycemia cannot be managed with diet alone.
Marketing Status approved
ATC Code A10BF02
DrugBank ID DB00491
KEGG ID D00625
MeSH ID C045621
PubChem ID 441314
TTD Drug ID D0D0ZD
NDC Product Code 76333-127; 71205-935; 71205-936; 76333-126; 71205-937; 69367-303; 69367-304; 67254-616; 57664-685; 65571-0010; 76333-125; 69367-305; 57664-684; 57664-686
UNII 0V5436JAQW
Synonyms miglitol | N-hydroxyethyl-1-desoxy-nojirimycin | N-hydroxyethyl-1-desoxynojirimycin | Diastabol | miglitol, 4-methylbenzenesulfonate salt, ((D)-isomer) | Plumarol | BAY m 1099 | BAY-m-1099 | BAY-m 1099 | Glyset
Chemical Information
Molecular Formula C8H17NO5
CAS Registry Number 72432-03-2
SMILES C1C(C(C(C(N1CCO)CO)O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Blood iron decreased13.11.01.006---
Constipation07.02.02.001--
Dermatitis23.03.04.002---
Diarrhoea07.02.01.001--
Flatulence07.01.04.002--
Gastrointestinal disorder07.11.01.001---
Gastrointestinal pain07.01.05.005--
Ileus07.13.01.001--
Ileus paralytic07.02.05.001---
Intestinal obstruction07.13.01.002---
Intestinal perforation07.04.06.002---
Intussusception07.13.01.008---
Nausea07.01.07.001--
Rash23.03.13.001---
Rectal haemorrhage07.12.03.001; 24.07.02.018--
Volvulus07.13.01.012---
Pneumoperitoneum07.07.01.008---
Subileus07.13.01.004---
Secretion discharge08.01.03.019---
Pneumatosis intestinalis07.11.01.043---
Intestinal haemorrhage07.12.03.005; 24.07.02.031---
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ADReCS-Target
Drug Name ADR Term Target
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