Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mianserin
Drug ID BADD_D01454
Description A tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of [mirtazapine].
Indications and Usage For the treatment of depression.
Marketing Status approved; investigational
ATC Code N06AX03
DrugBank ID DB06148
KEGG ID D08216
MeSH ID D008803
PubChem ID 4184
TTD Drug ID D0R6RO
NDC Product Code Not Available
UNII 250PJI13LM
Synonyms Mianserin | Mianserin Hydrochloride | Hydrochloride, Mianserin | Mianserin Monohydrochloride | Monohydrochloride, Mianserin | Tolvon | Lerivon | Org GB 94
Chemical Information
Molecular Formula C18H20N2
CAS Registry Number 24219-97-4
SMILES CN1CCN2C(C1)C3=CC=CC=C3CC4=CC=CC=C42
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agitation17.02.05.012; 19.06.02.001--
Agranulocytosis01.02.03.001---
Anaemia01.03.02.001--
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Asthenia08.01.01.001---
Bradycardia02.03.02.002---
Cardiac arrest02.03.04.001--
Cardiac failure02.05.01.001--
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Dermatitis23.03.04.002---
Diplopia06.02.06.002; 17.17.01.005---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Ear disorder04.03.01.001---
Electrocardiogram QT prolonged13.14.05.004--
Eye disorder06.08.03.001---
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014---
Gastrointestinal disorder07.11.01.001---
Gynaecomastia05.05.02.003; 21.05.04.003--
Headache17.14.01.001--
Hepatic function abnormal09.01.02.001---
Hepatitis09.01.07.004---
Hyperkinesia17.01.02.008---
Hypertension24.08.02.001--
Hypomania19.16.02.001---
Hypotension24.06.03.002--
Jaundice01.06.04.004; 09.01.01.004; 23.03.03.030---
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ADReCS-Target
Drug Name ADR Term Target
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