Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00096Alvimopan--
BADD_D00097Amantadine0.003066%
BADD_D00098Amantadine hydrochloride--
BADD_D00100Ambrisentan--
BADD_D00105Amiloride hydrochloride--
BADD_D00108Aminohippurate sodium--
BADD_D00115Amiodarone--
BADD_D00116Amiodarone hydrochloride--
BADD_D00117Amisulpride0.000131%
BADD_D00118Amitriptyline--
BADD_D00119Amitriptyline hydrochloride--
BADD_D00121Amlodipine--
BADD_D00122Amlodipine besylate--
BADD_D00126Amobarbital--
BADD_D00128Amoxapine--
BADD_D00130Amphetamine--
BADD_D00131Amphetamine sulfate--
BADD_D00132Amphotericin b--
BADD_D00139Anagrelide--
BADD_D00140Anagrelide hydrochloride--
BADD_D00142Anastrozole--
BADD_D00143Anidulafungin--
BADD_D00146Anti-thymocyte globulin (rabbit)--
BADD_D00152Apomorphine--
BADD_D00153Apomorphine hydrochloride--
BADD_D00154Apraclonidine--
BADD_D00157Aprepitant--
BADD_D00158Aprotinin (bovine)--
BADD_D00159Arformoterol--
BADD_D00160Arformoterol tartrate--
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