Drug Name |
Amitriptyline hydrochloride |
Drug ID |
BADD_D00119 |
Description |
Amitriptyline hydrochloride, also known as _Elavil_, is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain [A174658]. It was originally approved by the FDA in 1977 and manufactured by Sandoz [L5308]. |
Indications and Usage |
This drug in indicated for the following conditions [FDA label]:
Major depressive disorder in adults
Management of neuropathic pain in adults
Prophylactic treatment of chronic tension-type headache (CTTH) in adults
Prophylactic treatment of migraine in adults
Treatment of nocturnal enuresis in children aged 6 years and above when organic pathology, including spina bifida and related disorders, have been excluded and no response has been achieved to all other non-drug and drug treatments, including antispasmodics and vasopressin-related products. This product should only be prescribed by a healthcare professional with expertise in the management of persistent enuresis [FDA label]
Off-label uses: irritable bowel syndrome, sleep disorders, diabetic neuropathy, agitation, fibromyalgia, and insomnia |
Marketing Status |
approved |
ATC Code |
N06AA09 |
DrugBank ID |
DB00321
|
KEGG ID |
D00809
|
MeSH ID |
D000639
|
PubChem ID |
11065
|
TTD Drug ID |
D0Y5UG
|
NDC Product Code |
0781-1491; 0904-0202; 0904-7185; 76420-017; 16729-172; 29300-421; 50090-2553; 51655-969; 53002-3391; 53002-4910; 60760-212; 61919-117; 64330-630; 64330-632; 67296-1816; 67544-085; 70518-2570; 71335-0040; 71335-9635; 71335-9685; 72888-069; 72888-071; 0781-1486; 76420-239; 15894-0033; 17337-0501; 46438-0630; 54154-021; 63275-9936; 16571-108; 16714-260; 16714-449; 16714-450; 29300-419; 29300-423; 45865-648; 50090-6315; 50268-041; 55700-643; 57664-691; 63187-260; 63187-359; 63629-1368; 64330-634; 67296-0932; 67296-1279; 69844-063; 70518-1505; 70771-1177; 70934-071; 71335-9633; 0781-1489; 76420-238; 36974-0019; 16714-257; 16714-262; 16714-448; 29300-422; 43063-836; 55700-619; 57664-687; 60687-433; 60760-556; 61919-289; 63187-408; 68071-2843; 68071-4405; 70771-1176; 71335-0306; 71335-9710; 55289-124; 55700-600; 64330-635; 67296-0388; 68071-2796; 69306-050; 69844-060; 69844-062; 71205-466; 71335-0366; 71335-9668; 0904-7184; 38779-0189; 67763-104; 16571-106; 16571-110; 16714-261; 16714-446; 16729-174; 50090-3564; 51655-632; 51655-639; 61919-076; 67296-1509; 68788-6432; 68788-6825; 70518-1633; 70518-3654; 70710-1225; 71335-0173; 71335-0566; 72888-068; 72888-072; 0781-1488; 76420-237; 80425-0285; 80425-0287; 49452-0460; 16729-175; 16729-176; 43063-822; 50090-6179; 50268-039; 55700-689; 60687-444; 63187-156; 63187-637; 63629-8987; 68071-2931; 68071-2955; 68788-8218; 70518-1538; 70518-2258; 70518-3691; 70756-203; 70756-205; 70771-1178; 71610-695; 71610-710; 72789-305; 46438-0038; 71554-001; 29300-420; 50268-037; 51655-084; 55154-7898; 60760-181; 61919-374; 63187-229; 63629-2123; 64330-633; 67544-253; 68071-4238; 68071-4519; 70518-3621; 70934-607; 71335-9637; 71610-711; 0781-1487; 70859-013; 16571-105; 16714-258; 29300-424; 51655-121; 63629-2120; 68788-8339; 68788-8363; 70518-1484; 70518-3641; 70756-204; 70771-1174; 70934-703; 71610-703; 0904-0201; 83008-003; 83008-004; 51927-1603; 50268-038; 50268-040; 57664-689; 57664-690; 60760-367; 68788-6320; 70756-201; 70771-1175; 70934-428; 72189-309; 66577-038; 79572-002; 16571-107; 16714-259; 16729-171; 16729-173; 45865-432; 55700-660; 63187-155; 64330-631; 68071-4348; 68071-5220; 68788-6899; 68788-7061; 68788-8346; 68788-8380; 69844-058; 69844-059; 69844-061; 70710-1226; 70710-1227; 70710-1228; 70710-1229; 70710-1230; 70756-202; 70756-206; 70771-1173; 71335-0395; 71335-1254; 71335-1256; 72888-067; 72888-070; 0781-1490; 68981-015; 16571-109; 16714-447; 16714-451; 43063-863; 50090-2840; 50090-6313; 50090-6418; 51655-334; 57664-688; 57664-692 |
UNII |
26LUD4JO9K
|
Synonyms |
Amitriptyline | Tryptine | Amineurin | Amitrip | Amitriptylin Beta | Amitriptylin Desitin | Desitin, Amitriptylin | Amitriptylin RPh | RPh, Amitriptylin | Amitriptylin-Neuraxpharm | Amitriptylin Neuraxpharm | Amitriptyline Hydrochloride | Amitrol | Anapsique | Apo-Amitriptyline | Apo Amitriptyline | Damilen | Domical | Laroxyl | Lentizol | Novoprotect | Saroten | Sarotex | Syneudon | Triptafen | Endep | Tryptizol | Elavil | Tryptanol |