Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Autonomic nervous system disorders
ADR ID BADD_A00401
ADR Hierarchy
17      Nervous system disorders
17.05      Neuromuscular disorders
17.05.01      Autonomic nervous system disorders
Description Diseases of the parasympathetic or sympathetic divisions of the AUTONOMIC NERVOUS SYSTEM; which has components located in the CENTRAL NERVOUS SYSTEM and PERIPHERAL NERVOUS SYSTEM. Autonomic dysfunction may be associated with HYPOTHALAMIC DISEASES; BRAIN STEM disorders; SPINAL CORD DISEASES; and PERIPHERAL NERVOUS SYSTEM DISEASES. Manifestations include impairments of vegetative functions including the maintenance of BLOOD PRESSURE; HEART RATE; pupil function; SWEATING; REPRODUCTIVE AND URINARY PHYSIOLOGY; and DIGESTION. [MeSH]
MedDRA Code 10003839
MeSH ID D001342
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Autonomic Nervous System Diseases | Nervous System Diseases, Autonomic | Autonomic Central Nervous System Diseases | Central Autonomic Nervous System Diseases | ANS Diseases | ANS Disease | Autonomic Diseases | Autonomic Disease | Autonomic Nervous System Disorders | Disorders of the Autonomic Nervous System | ANS (Autonomic Nervous System) Diseases | Segmental Autonomic Dysfunction | Autonomic Dysfunction, Segmental | Autonomic Dysfunctions, Segmental | Segmental Autonomic Dysfunctions | Peripheral Autonomic Nervous System Diseases | Autonomic Peripheral Nervous System Diseases | Nervous System Diseases, Parasympathetic | Parasympathetic Nervous System Diseases | Nervous System Diseases, Sympathetic | Sympathetic Nervous System Diseases
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02396Zonisamide--
BADD_D02407Upadacitinib--
BADD_D02412Octreotide--
BADD_D02416Ropivacaine0.000179%
BADD_D02428Loperamide--
BADD_D02432Glycopyrronium0.002837%
BADD_D02439Levodopa--
BADD_D02440Lisdexamfetamine--
BADD_D02441Rasagiline0.002436%
BADD_D02443Tiotropium--
BADD_D02445Solifenacin0.000174%
BADD_D02451Pimavanserin--
BADD_D02456Vilazodone--
BADD_D02464Fingolimod0.000603%
BADD_D02470Nintedanib--
BADD_D02473Sodium chloride--
BADD_D02482Acalabrutinib--
BADD_D02484Istradefylline--
BADD_D02488Esketamine--
BADD_D02490Apalutamide0.000501%
BADD_D02491Valbenazine--
BADD_D02492Deflazacort--
BADD_D02504Lorlatinib--
BADD_D02510Rucaparib--
BADD_D02511Siponimod--
BADD_D02517Enasidenib--
BADD_D02539Calcium--
BADD_D02553Entrectinib--
BADD_D02556Ferrous cation--
BADD_D02558Gadolinium cation (3+)--
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