Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Rasagiline
Drug ID BADD_D02441
Description Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Indications and Usage For the treatment of the signs and symptoms of idiopathic Parkinsons disease as initial monotherapy and as adjunct therapy to levodopa.
Marketing Status approved
ATC Code N04BD02
DrugBank ID DB01367
KEGG ID D08469; D10829
MeSH ID C031967
PubChem ID 3052776
TTD Drug ID D06OMW
NDC Product Code 16714-770; 0093-3061; 67877-260; 47781-683; 42291-780; 67877-259; 16714-771; 0093-3060; 42571-221; 47781-690; 42571-220; 42291-779
UNII 003N66TS6T
Synonyms rasagiline | N-2-propynyl-1-indanamine | AGN 1135 | AGN-1135 | TVP 1022 | TVP1022 | TVP-1022 | N-propargyl-1-aminoindan mesylate | rasagiline hydrochloride | TVP 101 | TVP-101 | 2,3-dihydro-N-2-propynyl-1H-inden-1-amine-(1R)-hydrochloride | Azilect
Chemical Information
Molecular Formula C12H13N
CAS Registry Number 136236-51-6
SMILES C#CCNC1CCC2=CC=CC=C12
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acute myocardial infarction02.02.02.001; 24.04.04.0010.004871%-
Affective disorder19.04.04.0010.003572%-
Aggression19.05.01.0010.002436%-
Agitation17.02.05.012; 19.06.02.0010.006008%
Akinesia17.01.02.0030.002436%-
Altered state of consciousness17.02.04.001; 19.07.01.0030.005683%-
Amaurosis06.02.10.0010.001624%-
Angina pectoris02.02.02.002; 24.04.04.0020.001624%
Anxiety19.06.02.0020.017211%
Aphasia17.02.03.001; 19.21.01.0010.003247%
Aspiration22.02.07.0070.003247%
Asthenia08.01.01.0010.007307%-
Atrial fibrillation02.03.03.0020.007632%
Back pain15.03.04.0050.004059%
Blood pressure fluctuation24.06.01.0020.003247%-
Bradykinesia17.01.02.0040.002436%-
Cardiac arrest02.03.04.0010.003247%
Cardio-respiratory arrest02.03.04.002; 22.02.06.0070.001624%-
Cardiovascular disorder02.11.01.010; 24.03.02.0090.001624%-
Cerebral haemorrhage17.08.01.003; 24.07.04.0010.003247%-
Cerebral infarction17.08.01.004; 24.04.06.0020.004059%-
Cholecystitis acute09.03.01.0030.001624%-
Coma17.02.09.0010.002436%-
Completed suicide08.04.01.010; 19.12.01.0010.002436%-
Condition aggravated08.01.03.0040.022570%-
Confusional state17.02.03.005; 19.13.01.0010.005683%
Death08.04.01.0010.032474%
Decubitus ulcer23.03.11.0060.001624%-
Dehydration14.05.05.0010.007307%
Delirium19.13.02.0010.002436%
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