Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Anticholinergic syndrome
ADR ID BADD_A00266
ADR Hierarchy
17      Nervous system disorders
17.05      Neuromuscular disorders
17.05.01      Autonomic nervous system disorders
17.05.01.001      Anticholinergic syndrome
Description Adverse drug effects associated with CHOLINERGIC ANTAGONISTS. Clinical features include TACHYCARDIA; HYPERTHERMIA; MYDRIASIS, dry skin and dry mucous membranes, decreased bowel sounds and urinary retention in peripheral anticholinergic syndrome; and HALLUCINATIONS; PSYCHOSES; SEIZURES; and COMA in central anticholinergic syndrome. [MeSH]
MedDRA Code 10002757
MeSH ID D064807
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Anticholinergic syndrome | Atropine-like syndrome | Syndrome anticholinergic | Syndrome atropine-like | Syndrome parasympatholytic | Anticholinergic Syndrome | Anticholinergic Syndromes | Syndrome, Anticholinergic | Syndromes, Anticholinergic | Peripheral Anticholinergic Syndrome | Anticholinergic Syndrome, Peripheral | Anticholinergic Syndromes, Peripheral | Peripheral Anticholinergic Syndromes | Syndrome, Peripheral Anticholinergic | Syndromes, Peripheral Anticholinergic | Central Anticholinergic Syndrome | Anticholinergic Syndrome, Central | Anticholinergic Syndromes, Central | Central Anticholinergic Syndromes | Syndrome, Central Anticholinergic | Syndromes, Central Anticholinergic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00085Alprazolam0.000078%
BADD_D00189Atropine0.000620%
BADD_D00275Biperiden hydrochloride--
BADD_D00417Cetirizine0.000071%
BADD_D00499Clomipramine0.002898%
BADD_D00500Clomipramine hydrochloride--
BADD_D00501Clonazepam0.000059%
BADD_D00511Clozapine0.004280%
BADD_D00545Cyclobenzaprine0.000024%
BADD_D00547Cyclopentolate0.002448%
BADD_D00648Diazepam0.000076%
BADD_D00676Dimenhydrinate--
BADD_D00686Diphenhydramine0.002418%
BADD_D00809Escitalopram0.000051%
BADD_D00891Fesoterodine0.000992%
BADD_D00979Furosemide0.000028%
BADD_D01599Olanzapine0.003052%
BADD_D01656Paliperidone0.003415%
BADD_D01679Paroxetine--
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01835Pregabalin0.000182%
BADD_D01848Prochlorperazine--
BADD_D01854Promethazine0.000096%
BADD_D01864Propofol--
BADD_D01888Quetiapine0.000365%
BADD_D01951Risperidone0.001515%
BADD_D01994Scopolamine0.000663%
BADD_D02010Sertraline0.000019%
BADD_D02282Trifluoperazine hydrochloride--
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