Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mepivacaine hydrochloride
Drug ID BADD_D01388
Description A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Indications and Usage For production of local or regional analgesia and anesthesia by local infiltration, peripheral nerve block techniques, and central neural techniques including epidural and caudal blocks.
Marketing Status approved; vet_approved
ATC Code N01BB03
DrugBank ID DB00961
KEGG ID D00738
MeSH ID D008619
PubChem ID 66070
TTD Drug ID D0WO8W
NDC Product Code 67239-0201; 66975-406; 0404-6730; 52932-0731; 0362-1098; 63323-260; 66312-441; 42756-1080; 50227-1080; 66467-9760; 50090-4408; 63323-293; 63323-294; 63323-296; 0362-0753; 63323-283; 17381-261; 43128-005
UNII 4VFX2L7EM5
Synonyms Mepivacaine | Mepivacaina Braun | Isogaine | Meaverin | Mecain | Mepihexal | Mepivacain-Injektopas | Mepivacain Injektopas | Mepivacaine Hydrochloride | Mepivacaine Monohydrochloride | Mepivastesin | Polocaine | Scandinibsa | Scandonest | Scandicain | Scandicaine | Carbocaine | Carbocaïne | Isocaine
Chemical Information
Molecular Formula C15H23ClN2O
CAS Registry Number 1722-62-9
SMILES CC1=C(C(=CC=C1)C)NC(=O)C2CCCCN2C.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Brain hypoxia17.08.02.009; 22.02.02.010; 24.04.06.022---
Depressed level of consciousness17.02.04.002--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Loss of consciousness17.02.04.004---
Nervousness19.06.02.003---
Oedema08.01.07.006; 14.05.06.010---
Pulse abnormal13.14.04.004---
Respiratory arrest22.02.01.009---
Seizure17.12.03.001--
Skin lesion23.03.03.010---
Somnolence17.02.04.006; 19.02.05.003--
Swelling08.01.03.015---
Swelling face08.01.03.100; 10.01.05.018; 23.04.01.018---
Tremor17.01.06.002--
Urticaria10.01.06.001; 23.04.02.001--
Vision blurred06.02.06.007; 17.17.01.010--
Paraesthesia oral07.05.05.035; 17.02.06.008---
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