Drug Name |
Ifosfamide |
Drug ID |
BADD_D01133 |
Description |
Ifosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent. |
Indications and Usage |
Used as a component of various chemotherapeutic regimens as third-line therapy for recurrent or refractory germ cell testicular cancer. Also used as a component of various chemotherapeutic regimens for the treatment of cervical cancer, as well as in conjunction with surgery and/or radiation therapy in the treatment of various soft tissue sarcomas. Other indications include treatment of osteosarcoma, bladder cancer, ovarian cancer. small cell lung cancer, and non-Hodgkin's lymphoma. |
Marketing Status |
approved |
ATC Code |
L01AA06 |
DrugBank ID |
DB01181
|
KEGG ID |
D00343
|
MeSH ID |
D007069
|
PubChem ID |
3690
|
TTD Drug ID |
D02TLO
|
NDC Product Code |
10019-925; 57884-0006; 63323-142; 0143-9531; 0338-3991; 15308-0411; 0338-3993; 65124-0001; 0143-9530; 10019-926; 10019-927; 10019-929 |
UNII |
UM20QQM95Y
|
Synonyms |
Ifosfamide | Isofosfamide | Isophosphamide | Iphosphamide | Iso-Endoxan | Iso Endoxan | Holoxan | NSC-109,724 | NSC 109,724 | NSC109,724 | NSC-109724 | NSC 109724 | NSC109724 | Asta Z 4942 |