Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Oligospermia
ADR ID BADD_A03161
ADR Hierarchy
21      Reproductive system and breast disorders
21.03      Sexual function and fertility disorders
21.03.03      Spermatogenesis and semen disorders
21.03.03.005      Oligospermia
Description A disorder characterized by a decrease in the number of spermatozoa in the semen. [CTCAE] A condition of suboptimal concentration of SPERMATOZOA in the ejaculated SEMEN to ensure successful FERTILIZATION of an OVUM. In humans, oligospermia is defined as a sperm count below 20 million per milliliter semen. [MeSH]
MedDRA Code 10030300
MeSH ID D009845
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Oligospermia | Oligozoospermia | Hypospermatogenesis | Hypospermatogeneses | Low Sperm Count | Low Sperm Counts | Sperm Count, Low | Sperm Counts, Low | Oligoasthenoteratozoospermia | Oligoasthenoteratozoospermias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00285Bosentan--
BADD_D00518Colchicine--
BADD_D00549Cyclophosphamide--
BADD_D00723Doxorubicin--
BADD_D00898Finasteride0.000845%
BADD_D00932Fluoxetine--
BADD_D00934Fluoxymesterone--
BADD_D01010Gemcitabine hydrochloride--
BADD_D01110Hydroxyurea--
BADD_D01119Ibrutinib0.000660%
BADD_D01133Ifosfamide--
BADD_D01230Ketoconazole--
BADD_D01392Mercaptopurine--
BADD_D01397Mesalamine--
BADD_D01418Methotrexate--
BADD_D01438Methyltestosterone--
BADD_D01529Nandrolone--
BADD_D01530Nandrolone decanoate--
BADD_D01634Oxandrolone--
BADD_D01647Oxymetholone--
BADD_D02093Sulfasalazine--
BADD_D02170Testosterone--
BADD_D02171Testosterone cypionate--
BADD_D02172Testosterone enanthate--
BADD_D02173Testosterone propionate--
BADD_D02174Testosterone undecanoate--
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